Azido-PEG5-amine

Modify Date: 2024-01-02 08:52:20

Azido-PEG5-amine Structure
Azido-PEG5-amine structure
Common Name Azido-PEG5-amine
CAS Number 516493-93-9 Molecular Weight 306.35900
Density N/A Boiling Point N/A
Molecular Formula C12H26N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG5-amine


Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonym More Synonyms

 Azido-PEG5-amine Biological Activity

Description Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H26N4O5
Molecular Weight 306.35900
Exact Mass 306.19000
PSA 121.92000
LogP 0.49146
Storage condition 2-8°C

 Synonyms

17-azido-3,6,9,12,15-pentaoxaheptadecanamine
5-PEG amino azide
17-azido-3,6,9,12,15-pentaoxa-1-heptadecylamine
17-azide-3,6,9,12,15-pentaoxaheptadecan-1-amine
Azido-PEG5-Amine
17-AZIDO-3,6,9,12,15-PENTAOXAHEPTADECAN-1-AMINE
1-amino-17-azido-3,6,9,12,15-pentaoxaheptadecane
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