Tiotropium bromide
Modify Date: 2024-01-01 20:11:12
Tiotropium bromide structure
|
Common Name | Tiotropium bromide | ||
|---|---|---|---|---|
| CAS Number | 136310-93-5 | Molecular Weight | 472.416 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H22BrNO4S2 | Melting Point | 218-2200C | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tiotropium bromideTiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. |
| Name | Tiotropium Bromide |
|---|---|
| Synonym | More Synonyms |
| Description | Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. |
|---|---|
| Related Catalog | |
| Target |
mAChR |
| In Vitro | Tiotropium Bromide stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure. |
| References |
[1]. Barnes PJ. Tiotropium bromide. Expert Opin Investig Drugs. 2001 Apr;10(4):733-40. [3]. Lipson DA. Tiotropium bromide. Int J Chron Obstruct Pulmon Dis. 2006;1(2):107-14. |
| Melting Point | 218-2200C |
|---|---|
| Molecular Formula | C19H22BrNO4S2 |
| Molecular Weight | 472.416 |
| Exact Mass | 471.017365 |
| PSA | 115.54000 |
| Storage condition | Refrigerator |
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36:Irritating to the eyes. |
| Safety Phrases | S23-S24/25 |
| WGK Germany | 3 |
| HS Code | 29309070 |
| HS Code | 29309070 |
|---|
| Tiova |
| 3-Oxa-9-azoniatricyclo[3.3.1.0]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide, (1R,2R,4S,5S)- (1:1) |
| MFCD00867027 |
| (1a,2b,4b,5a,7b)-7-[(Hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0 2,4 ]nonane bromide |
| BA 679 BR |
| (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0]nonane bromide |
| 6b,7b-Epoxy-3b-hydroxy-8-methyl-1aH,5aH-tropanium bromide di-2-thienylglycolate |
| Spiriva Handihaler |
| TIOTROPIUM BROMIDE |
| (1R,2R,4S,5S,7s)-7-[2-Hydroxy(di-2-thienyl)acetoxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0]nonane bromide |
| Spiriva |
| Tiotropium (Bromide) |
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Price: ￥257.4/25mg
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