DBCO-Sulfo-Link-biotin

Modify Date: 2025-08-26 20:03:51

DBCO-Sulfo-Link-biotin Structure
DBCO-Sulfo-Link-biotin structure
Common Name DBCO-Sulfo-Link-biotin
CAS Number 1363444-70-5 Molecular Weight 653.77
Density N/A Boiling Point N/A
Molecular Formula C31H35N5O7S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-Sulfo-Link-biotin


DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name DBCO-Sulfo-Link-biotin

 DBCO-Sulfo-Link-biotin Biological Activity

Description DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Portnoff AD, et al. An antidote approach to reduce risk and broaden utility of antibody-based therapeutics. J Biol Chem. 2017 May 19;292(20):8498-8506.

 Chemical & Physical Properties

Molecular Formula C31H35N5O7S2
Molecular Weight 653.77
InChIKey XDEWKDCHVSWNBX-MXGHRJRVSA-N
SMILES O=C(CCCCC1SCC2NC(=O)NC21)NCC(C(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc21)S(=O)(=O)O
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