1-Dehydro-[10]-gingerdione

Modify Date: 2024-01-04 13:21:37

1-Dehydro-[10]-gingerdione structure	Common Name	1-Dehydro-[10]-gingerdione
	CAS Number	136826-50-1	Molecular Weight	346.461
	Density	1.1±0.1 g/cm3	Boiling Point	495.2±40.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₃₀O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	166.3±20.8 °C

Use of 1-Dehydro-[10]-gingerdione

1-Dehydro-[10]-gingerdione directly inhibits IKKβ activity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS-induced NF-κB transcriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research[1].

Name	1-Dehydro-10-gingerdione
Synonym	More Synonyms

Description	1-Dehydro-[10]-gingerdione directly inhibits IKKβ activity by targeting the activation loop of IKKβ, thus disrupting IKKβ-catalysed IκBα phosphorylation in macrophages stimulated with agonists. 1-Dehydro-[10]-gingerdione inhibits LPS-induced NF-κB transcriptional activity. 1-Dehydro-[10]-gingerdione has the potential for NF-κB-associated inflammation and autoimmune disorders research[1].
Related Catalog	Signaling Pathways >> NF-κB >> IKK Research Areas >> Inflammation/Immunology
References	[1]. Hwa Young Lee, et al. 1-Dehydro-[10]-gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes. Br J Pharmacol. 2012 Sep;167(1):128-40.

Density	1.1±0.1 g/cm3
Boiling Point	495.2±40.0 °C at 760 mmHg
Molecular Formula	C₂₁H₃₀O₄
Molecular Weight	346.461
Flash Point	166.3±20.8 °C
Exact Mass	346.214417
LogP	5.51
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.531

1-Tetradecene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-, (1E)-

(1E)-1-(4-Hydroxy-3-methoxyphenyl)-1-tetradecene-3,5-dione

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1-Dehydro-[10]-gingerdione
Price: ￥3438.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

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1-Dehydro-[10]-gingerdione

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