LY 215840
Modify Date: 2024-04-04 18:42:26
LY 215840 structure
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Common Name | LY 215840 | ||
|---|---|---|---|---|
| CAS Number | 137328-52-0 | Molecular Weight | 395.54 | |
| Density | 1.34g/cm3 | Boiling Point | 642.1ºC at 760mmHg | |
| Molecular Formula | C24H33N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 342.1ºC | |
Use of LY 215840LY215840, a 5-HT7 receptor ligand and a 5-HT2 receptor antagonist, blocks serotonin-induced relaxation in canine coronary artery[1][2]. |
| Name | (6aR,9R)-N-[(1S,2R)-2-hydroxycyclopentyl]-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-carboxamide |
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| Synonym | More Synonyms |
| Description | LY215840, a 5-HT7 receptor ligand and a 5-HT2 receptor antagonist, blocks serotonin-induced relaxation in canine coronary artery[1][2]. |
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| Related Catalog | |
| Target |
5-HT2 Receptor 5-HT7 Receptor |
| In Vitro | LY215840 (1 μM) markedly potentiated contraction to 5-carboxamidotryptamine, the most potent coronary relaxant agonist and the agonist with the highest 5-HT7 receptor affinity[1]. LY215840 (3 x 10-10 to 10-8 M) blocks 5-HT2 receptors mediating contraction to 5-HT in vitro[2]. |
| References |
| Density | 1.34g/cm3 |
|---|---|
| Boiling Point | 642.1ºC at 760mmHg |
| Molecular Formula | C24H33N3O2 |
| Molecular Weight | 395.54 |
| Flash Point | 342.1ºC |
| Exact Mass | 395.25700 |
| PSA | 60.99000 |
| LogP | 3.99000 |
| Vapour Pressure | 2.3E-17mmHg at 25°C |
| Index of Refraction | 1.689 |
| [Orn8]-Urotensin II |
| Ergoline-8-carboxamide,N-(2-hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)-,(8beta(1S,2R)) |
| Ergoline-8-carboximide,N-(2-hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)-,(8beta(1S,2R)) |
| (4R,7R)-N-[(1S,2R)-2-hydroxycyclopentyl]-6-methyl-11-(propan-2-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carboxamide |