Factor D inhibitor 6
Modify Date: 2023-01-20 01:41:46
Factor D inhibitor 6 structure
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Common Name | Factor D inhibitor 6 | ||
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| CAS Number | 1386455-51-1 | Molecular Weight | 484.916 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H22ClFN6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Factor D inhibitor 6Factor D inhibitor 6 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 30 nM; is highly selective for human FD, showing no inhibition of factor B; efficiently block alternative pathway activation and prevent both C3 deposition onto, and lysis of, PNH erythrocytes; inhibits lipopolysaccharide-induced AP activation in FD-humanized mice. |
| Name | Factor D inhibitor 6 |
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| Description | Factor D inhibitor 6 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 30 nM; is highly selective for human FD, showing no inhibition of factor B; efficiently block alternative pathway activation and prevent both C3 deposition onto, and lysis of, PNH erythrocytes; inhibits lipopolysaccharide-induced AP activation in FD-humanized mice. |
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| References | References 1. Maibaum J, et al. Nat Chem Biol. 2016 Dec;12(12):1105-1110. View Related Products by Target Complement System |
| Molecular Formula | C23H22ClFN6O3 |
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| Molecular Weight | 484.916 |