4,4'-Thiodianiline

Modify Date: 2024-01-03 13:52:05

4,4'-Thiodianiline structure	Common Name	4,4'-Thiodianiline
	CAS Number	139-65-1	Molecular Weight	216.302
	Density	1.3±0.1 g/cm3	Boiling Point	464.8±30.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₁₂N₂S	Melting Point	105-107 °C(lit.)
	MSDS	Chinese USA	Flash Point	234.9±24.6 °C
	Symbol	GHS07, GHS08, GHS09	Signal Word	Danger

Name	4,4'-thiodianiline
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Boiling Point	464.8±30.0 °C at 760 mmHg
Melting Point	105-107 °C(lit.)
Molecular Formula	C₁₂H₁₂N₂S
Molecular Weight	216.302
Flash Point	234.9±24.6 °C
Exact Mass	216.072113
PSA	77.34000
LogP	2.18
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.707
Storage condition	-20°C

4,4'-Thiodianiline MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BY9625000

CHEMICAL NAME :: Aniline, 4,4'-thiodi-

CAS REGISTRY NUMBER :: 139-65-1

BEILSTEIN REFERENCE NO. :: 1875513

LAST UPDATED :: 199701

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C12-H12-N2-S

MOLECULAR WEIGHT :: 216.32

WISWESSER LINE NOTATION :: ZR DSR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3600 mg/kg/27D-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 113 gm/kg/54W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Endocrine - thyroid tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37 gm/kg/70W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Endocrine - thyroid tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 74 gm/kg/70W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Endocrine - thyroid tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 328 gm/kg/70W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Endocrine - thyroid tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 963 gm/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1925 gm/kg/77W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 510 gm/kg/68W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Endocrine - thyroid tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1020 gm/kg/68W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Endocrine - thyroid tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg/30D-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2000 mg/kg/30D-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1005 mg/kg/52W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 250 mg/kg

SEX/DURATION :: female 1-5 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 ug/plate

REFERENCE :: IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases. (POB 1097, Bloomfield, NJ 07003) V.1- 1933- Volume(issue)/page/year: 51,45,1983 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,147,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,147,1982 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993

Symbol	GHS07, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H302-H350-H411
Precautionary Statements	P201-P273-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;N: Dangerous for the environment;
Risk Phrases	R45;R22;R51/53
Safety Phrases	S53-S45-S61
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	BY9625000
Hazard Class	9.0

Precursor 9
CAS#:540-37-4 4-Iodoaniline CAS#:100-00-5 4-Chloronitrobenzene CAS#:1193-02-8 4-Aminothiophenol CAS#:1223-31-0 di(p-Nitropheny...
CAS#:101-59-7 p-[(p-Nitrophen... CAS#:586-78-7 1-Bromo-4-nitro... CAS#:142-04-1 Anilinium chloride CAS#:7704-34-9 Sulfur
CAS#:722-27-0 4-Aminophenyl d...
DownStream 10
CAS#:4430-49-3 Benzene,1,1'-su... CAS#:139-66-2 Diphenylsulfid CAS#:7664-93-9 Sulfuric acid CAS#:88-89-1 Trinitrophenol
CAS#:80-08-0 4,4'-Diaminodip... CAS#:2664-63-3 4,4′-Thiodiphenol CAS#:5181-10-2 bis(4-chlorophe... CAS#:3393-78-0 Benzene,1,1'-th...
CAS#:13604-44-9 4-[4-(dimethyla... CAS#:162781-32-0 1-phenyl-3-[4-[...

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above u...

In vivo evaluation of diaminodiphenyls: anticonvulsant agents with minimal acute neurotoxicity.

Bioorg. Med. Chem. Lett. 19 , 5012-5, (2009)

Several diaminodiphenyl analogs were assessed in vivo for their capacity to inhibit seizure induction and propagation in rodents. Both 3,4'- and 4,4'-diaminodiphenyl compounds prevented seizures for a...

DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by four rat thyroid carcinogens.

Toxicol. Appl. Pharmacol. 203(2) , 99-105, (2005)

Four chemicals that are known to induce in rats thyroid follicular-cell adenomas and carcinomas were assayed for their ability to induce DNA damage and DNA repair synthesis in primary cultures of huma...

4,4'-Diamino diphenyl sulfide

4,4'-Sulfanediyldianiline

EINECS 205-370-9

4-(4-aminophenyl)sulfanylaniline

Benzenamine, 4,4'-thiobis-

MFCD00025342

Bis(4-aMinophenyl) Sulfide

4,4'-Thiodianiline

4-Aminophenyl Sulfide

4,4′-Thiodianiline

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4,4'-Thiodianiline
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 4,4'-Thiodianiline
Price: ￥1398.0/25g ￥408.0/5g ￥398.0/250mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: bis-(4-Aminophenyl) sulfide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

4,4'-Thiodianiline suppliers

4,4'-Thiodianiline price

4,4'-Thiodianiline

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Articles11

Synonyms