4-Aminophenyl disulfide

Modify Date: 2025-08-26 16:34:45

4-Aminophenyl disulfide Structure
4-Aminophenyl disulfide structure
Common Name 4-Aminophenyl disulfide
CAS Number 722-27-0 Molecular Weight 248.367
Density 1.3±0.1 g/cm3 Boiling Point 447.0±30.0 °C at 760 mmHg
Molecular Formula C12H12N2S2 Melting Point 77-78 °C(lit.)
MSDS USA Flash Point 224.2±24.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4,4'-Dithiodianiline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 447.0±30.0 °C at 760 mmHg
Melting Point 77-78 °C(lit.)
Molecular Formula C12H12N2S2
Molecular Weight 248.367
Flash Point 224.2±24.6 °C
Exact Mass 248.044189
PSA 102.64000
LogP 1.65
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.741
Stability Stable. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents. Sensitive to air.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BX9580000
CHEMICAL NAME :
Aniline, p,p'-dithiodi-
CAS REGISTRY NUMBER :
722-27-0
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C12-H12-N2-S2
MOLECULAR WEIGHT :
248.38
WISWESSER LINE NOTATION :
ZR DSSR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
434 mg/kg/7D-I
TOXIC EFFECTS :
Endocrine - changes in adrenal weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - changes in iron

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,123,1979

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS BX9580000
Hazard Class 9.0
HS Code 2930909090

 Synthetic Route

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles2

More Articles
Elevated glutathione accelerates oxidative damage to erythrocytes produced by aromatic disulfide.

Blood 73(1) , 312-7, (1989)

It has been shown that certain dogs have erythrocytes characterized by an inherited high concentration of reduced glutathione (GSH), five to seven times the normal level (high-GSH RBCs). We examined w...

Kinetics of polymerization of hemoglobin S modified by thiol reagents and by oxidation.

Biochim. Biophys. Acta 830(1) , 71-9, (1985)

The effects of four thiol reagents on the kinetics of polymerization of hemoglobin S have been studied in high phosphate buffer (1.8 M), in the presence (3 mM) or absence of sodium dithionite, dependi...

 Synonyms

Dithioaniline
4,4'-Diaminodiphenyl disulphide
4-Aminophenyl disulfide
p-p'-Dithiodianiline
4,4'-Dithio-Aniline
4-aminophenyl
{4-[(4-Aminophenyl)dithio]phenyl}amine
4,4'-Disulfanediyldianiline
MFCD00007882
Benzenamine, 4,4'-dithiobis-
EINECS 211-961-2
4,4'-diamino diphenyl disulfide
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