4-Aminophenyl disulfide
4-Aminophenyl disulfide structure
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Common Name | 4-Aminophenyl disulfide | ||
|---|---|---|---|---|
| CAS Number | 722-27-0 | Molecular Weight | 248.367 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 447.0±30.0 °C at 760 mmHg | |
| Molecular Formula | C12H12N2S2 | Melting Point | 77-78 °C(lit.) | |
| MSDS | USA | Flash Point | 224.2±24.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Summary: 4,4'-Dithiodianiline (4,4'-Dithiodianiline)，also known as 4-Aminophenyl disulfide, has a CAS number of 722-27-0. Its molecular formula is C12H12N2S2, with a molecular weight of 248.367. It appears as a yellow powder with a melting point of 77-78°C and a boiling point of 447.0±30.0°C, and a density of 1.3±0.1g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4,4'-Dithiodianiline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 447.0±30.0 °C at 760 mmHg |
| Melting Point | 77-78 °C(lit.) |
| Molecular Formula | C12H12N2S2 |
| Molecular Weight | 248.367 |
| Flash Point | 224.2±24.6 °C |
| Exact Mass | 248.044189 |
| PSA | 102.64000 |
| LogP | 1.65 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.741 |
| InChIKey | MERLDGDYUMSLAY-UHFFFAOYSA-N |
| SMILES | Nc1ccc(SSc2ccc(N)cc2)cc1 |
| Stability | Stable. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents. Sensitive to air. |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | BX9580000 |
| Hazard Class | 9.0 |
| HS Code | 2930909090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 10 | |
CAS#:540-37-4
CAS#:22948-02-3
CAS#:2987-46-4
CAS#:1193-02-8
CAS#:100-00-5
CAS#:350-46-9
CAS#:100-32-3
CAS#:1223-31-0
CAS#:106-47-8![1-isocyanato-4-[(4-isocyanatophenyl)disulfanyl]benzene structure](https://image.chemsrc.com/caspic/182/20929-84-4.png)
CAS#:20929-84-4
CAS#:213013-97-9
CAS#:624-39-5
CAS#:10352-44-0
CAS#:139-65-1
CAS#:1135-14-4
CAS#:1126-81-4
CAS#:106-53-6![1-(2-chloroethyl)-3-[4-[4-(2-chloroethylcarbamoylamino)phenyl]disulfanylphenyl]urea structure](https://image.chemsrc.com/caspic/326/13908-73-1.png)
CAS#:13908-73-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Elevated glutathione accelerates oxidative damage to erythrocytes produced by aromatic disulfide.
Blood 73(1) , 312-7, (1989) It has been shown that certain dogs have erythrocytes characterized by an inherited high concentration of reduced glutathione (GSH), five to seven times the normal level (high-GSH RBCs). We examined w... |
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Kinetics of polymerization of hemoglobin S modified by thiol reagents and by oxidation.
Biochim. Biophys. Acta 830(1) , 71-9, (1985) The effects of four thiol reagents on the kinetics of polymerization of hemoglobin S have been studied in high phosphate buffer (1.8 M), in the presence (3 mM) or absence of sodium dithionite, dependi... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of HIV-1 replication in human T-cell by using XTT assay; Inactive
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL693364
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Name: Inhibition of HIV-1 replication in a proliferating human T-cell line assayed using an...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL697213
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Name: Binding affinity to recombinant Ebola virus Zaire Mayinga-76 Envelope glycoprotein as...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4401872
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Dithioaniline |
| 4,4'-Diaminodiphenyl disulphide |
| 4-Aminophenyl disulfide |
| p-p'-Dithiodianiline |
| 4,4'-Dithio-Aniline |
| 4-aminophenyl |
| {4-[(4-Aminophenyl)dithio]phenyl}amine |
| 4,4'-Disulfanediyldianiline |
| MFCD00007882 |
| EINECS 211-961-2 |
| 4,4'-diamino diphenyl disulfide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the downstream products of 4,4'-Dithiodianiline? |
| A: Related downstream products(CAS) of 4,4'-Dithiodianiline: 20929-84-4;213013-97-9;624-39-5;10352-44-0;139-65-1;1135-14-4;1126-81-4;1193-02-8;106-53-6;13908-73-1. |
| Q: What is the boiling point of 4,4'-Dithiodianiline? |
| A: Boiling point of 4,4'-Dithiodianiline is 447.0±30.0 °C at 760 mmHg. |
| Q: What is the molecular weight of 4,4'-Dithiodianiline? |
| A: Molecular weight of 4,4'-Dithiodianiline is 248.367. |
| Q: What is the English name of 4,4'-Dithiodianiline? |
| A: The English name of 4,4'-Dithiodianiline is 4,4'-Dithiodianiline. |
| Q: What is the molecular formula of 4,4'-Dithiodianiline? |
| A: Molecular formula of 4,4'-Dithiodianiline is C12H12N2S2. |
| Q: What is the LogP of 4,4'-Dithiodianiline? |
| A: LogP of 4,4'-Dithiodianiline is 1.65. |
| Q: What are the upstream materials of 4,4'-Dithiodianiline? |
| A: Related upstream materials(CAS) of 4,4'-Dithiodianiline: 540-37-4;22948-02-3;2987-46-4;1193-02-8;100-00-5;350-46-9;100-32-3;1223-31-0;106-47-8. |
| Q: What English synonyms does 4,4'-Dithiodianiline have? |
| A: English synonyms of 4,4'-Dithiodianiline: Dithioaniline, 4,4'-Diaminodiphenyl disulphide, 4-Aminophenyl disulfide, p-p'-Dithiodianiline, 4,4'-Dithio-Aniline, 4-aminophenyl, {4-[(4-Aminophenyl)dithio]phenyl}amine, 4,4'-Disulfanediyldianiline, MFCD00007882, EINECS 211-961-2, 4,4'-diamino diphenyl disulfide. |
| Q: What is the safety information for 4,4'-Dithiodianiline? |
| A: Safety information for 4,4'-Dithiodianiline: S26-S36. |
| Q: What is the melting point of 4,4'-Dithiodianiline? |
| A: Melting point of 4,4'-Dithiodianiline is 77-78 °C(lit.). |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |