Carmine

Modify Date: 2024-01-02 16:21:59

Carmine Structure
Carmine structure
Common Name Carmine
CAS Number 1390-65-4 Molecular Weight 492.386
Density 1.9±0.1 g/cm3 Boiling Point 907.6±65.0 °C at 760 mmHg
Molecular Formula C22H20O13 Melting Point 136ºC dec
MSDS Chinese USA Flash Point 316.1±27.8 °C

 Use of Carmine


Carmine (Carmine red), a "semi-synthetic" dye, is a complex of aluminum and the natural dye Cochineal (Carminic acid). Cochineal is isolated from the native Mexican and South American insect. Carmine is a widely used "natural" food additive. Carmine provokes both an immediate hypersensitivity and a delayed systemic response with cutaneous expression[1][2].

 Names

Name carmine
Synonym More Synonyms

 Carmine Biological Activity

Description Carmine (Carmine red), a "semi-synthetic" dye, is a complex of aluminum and the natural dye Cochineal (Carminic acid). Cochineal is isolated from the native Mexican and South American insect. Carmine is a widely used "natural" food additive. Carmine provokes both an immediate hypersensitivity and a delayed systemic response with cutaneous expression[1][2].
Related Catalog
In Vitro Carmine has been used in biological staining to demonstrate selectively nuclei, chromosomes or mucins, depending on the formulation[2].
References

[1]. Chandler W Rundle, et al. Contact Dermatitis to Carmine. Dermatitis. Sep/Oct 2018;29(5):244-249.

[2]. R W Dapson, et al. The history, chemistry and modes of action of carmine and related dyes. Biotech Histochem. 2007 Aug;82(4-5):173-87.

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 907.6±65.0 °C at 760 mmHg
Melting Point 136ºC dec
Molecular Formula C22H20O13
Molecular Weight 492.386
Flash Point 316.1±27.8 °C
Exact Mass 492.090393
PSA 256.66000
LogP 4.80
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.792
Storage condition Store at +5°C to +30°C.
Water Solubility ammonium hydroxide: soluble1mg/mL

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FH8891000
CHEMICAL NAME :
Carmine
CAS REGISTRY NUMBER :
1390-65-4
LAST UPDATED :
199504

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS FH8891000

 Articles6

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Transcriptome analysis of the hormone-sensing cells in mammary epithelial reveals dynamic changes in early pregnancy.

BMC Dev. Biol. 15 , 7, (2015)

Alveoli, the milk-producing units of the mammary gland, are generated during pregnancy by collaboration of different epithelial cell types. We present the first analysis of transcriptional changes wit...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

 Synonyms

(1S)-1,5-Anhydro-1-(7-carboxy-1,3,4,6-tetrahydroxy-8-methyl-9,10-dioxo-9,10-dihydro-2-anthracenyl)-D-glucitol
D-Glucitol, 1,5-anhydro-1-C-(7-carboxy-9,10-dihydro-1,3,4,6-tetrahydroxy-8-methyl-9,10-dioxo-2-anthracenyl)-, (1S)-
Carmine,high purity biol.stain,alum lake of carminic acid
MFCD00167028
Carmine Red
Broseliquid
rougerecd
EINECS 215-724-4
Carmine,certified,alum lake of carminic acid
Alum lake of carminic acid,Cochineal,Nacarat
2-Anthracenecarboxylic acid, 7-β-D-glucopyranosyl-9,10-dihydro-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-
(1S)-1,5-Anhydro-1-(7-carboxy-1,3,4,6-tetrahydroxy-8-methyl-9,10-dioxo-9,10-dihydroanthracen-2-yl)-D-glucitol
CARMINIC ACID
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