Rivaroxaban Impurity 3

Modify Date: 2025-08-25 13:02:03

Rivaroxaban Impurity 3 Structure
Rivaroxaban Impurity 3 structure
 Common Name Rivaroxaban Impurity 3
CAS Number 1415566-28-7 Molecular Weight 401.44
Density 1.400±0.06 g/cm3 (20 ºC 760 Torr) Boiling Point 758.0±60.0 °C(Predicted)
Molecular Formula C19H19N3O5S Melting Point 216-218 °C
MSDS N/A Flash Point N/A

 Use of Rivaroxaban Impurity 3


Dechloro Rivaroxaban is a highly selective, orally active inhibitor of Factor Xa. Dechloro Rivaroxaban inhibits human free FXa with a Ki of 0.4 nM. Dechloro Rivaroxaban inhibits prothrombinase activity and fibrin-associated FXa activity with IC50s of 2.1 nM and 92 nM, respectively[1].

 Names

Name Rivaroxaban Impurity 3
Synonym More Synonyms

 Rivaroxaban Impurity 3 Biological Activity

Description Dechloro Rivaroxaban is a highly selective, orally active inhibitor of Factor Xa. Dechloro Rivaroxaban inhibits human free FXa with a Ki of 0.4 nM. Dechloro Rivaroxaban inhibits prothrombinase activity and fibrin-associated FXa activity with IC50s of 2.1 nM and 92 nM, respectively[1].
Related Catalog
References

[1]. Lang D, et al. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans. Drug Metab Dispos. 2009 May;37(5):1046-55.  

 Chemical & Physical Properties

Density 1.400±0.06 g/cm3 (20 ºC 760 Torr)
Boiling Point 758.0±60.0 °C(Predicted)
Melting Point 216-218 °C
Molecular Formula C19H19N3O5S
Molecular Weight 401.44

 Synonyms

N-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
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