Mutant IDH1-IN-4 structure
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Common Name | Mutant IDH1-IN-4 | ||
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CAS Number | 1416270-18-2 | Molecular Weight | 438.56246 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C25H34N4O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Mutant IDH1-IN-4Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1]. |
Name | (R)-8-cyclopropyl-6-(3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl)-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridine-5-carbonitrile |
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Description | Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1]. |
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Related Catalog | |
Target |
IC50: ≤ 0.5 μM (mutant IDH 1 in cells)[1]. |
References |
[1]. US20170210749A1. |
Molecular Formula | C25H34N4O3 |
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Molecular Weight | 438.56246 |