Mutant IDH1-IN-2

Modify Date: 2024-01-09 15:44:25

Mutant IDH1-IN-2 structure	Common Name	Mutant IDH1-IN-2
	CAS Number	1429176-69-1	Molecular Weight	459.532
	Density	1.3±0.1 g/cm3	Boiling Point	578.1±60.0 °C at 760 mmHg
	Molecular Formula	C₂₄H₃₁F₂N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	303.4±32.9 °C

Use of Mutant IDH1-IN-2

Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay.Target: Mutant IDH1Mutant IDH1-IN-2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer. More bioactivity information in Patent WO 2013046136A1 (Example 224).

Name	Mutant IDH1-IN-2
Synonym	More Synonyms

Description	Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay.Target: Mutant IDH1Mutant IDH1-IN-2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer. More bioactivity information in Patent WO 2013046136A1 (Example 224).
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH) Research Areas >> Cancer
References	[1]. Huangshu, et al. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation

Density	1.3±0.1 g/cm3
Boiling Point	578.1±60.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₁F₂N₅O₂
Molecular Weight	459.532
Flash Point	303.4±32.9 °C
Exact Mass	459.244568
LogP	2.72
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.587
Storage condition	2-8℃

(4S)-3-(2-{[(1S)-1-{4-[(4,4-Difluoro-1-piperidinyl)methyl]phenyl}ethyl]amino}-4-pyrimidinyl)-4-isopropyl-1,3-oxazolidin-2-one

2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4,4-difluoro-1-piperidinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Mutant IDH1-IN-2
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Mutant IDH1-IN-2 suppliers

Price: $462/10mM*1mLinDMSO

Reference only. check more Mutant IDH1-IN-2 price

Mutant IDH1-IN-2

Use of Mutant IDH1-IN-2

Names

Mutant IDH1-IN-2 Biological Activity

Chemical & Physical Properties

Synonyms