GR 94800 TFA

Modify Date: 2024-01-16 14:14:14

GR 94800 TFA structure	Common Name	GR 94800 TFA
	CAS Number	141636-65-9	Molecular Weight	904.06400
	Density	1.282 g/cm3	Boiling Point	1310.4ºC at 760 mmHg
	Molecular Formula	C₄₉H₆₁N₉O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	746.3ºC

Use of GR 94800 TFA

GR 94800 is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively[1][2].

Name	(2S)-N-[(2S)-1-amino-1-oxohexan-2-yl]-1-[(2R)-1-[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-benzamidopropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide
Synonym	More Synonyms

Description	GR 94800 is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
In Vitro	Responses to EFS (15 Hz) were significantly reduced by the NK2 receptor antagonist GR 94800 (1 μM) either alone or in combination with the NK1 antagonist (1 μM)[3].
References	[1]. A B McElroy, et al. Highly potent and selective heptapeptide antagonists of the neurokinin NK-2 receptor. J Med Chem. 1992 Jul 10;35(14):2582-91. [2]. M A Matuszek, et al. An investigation of tachykinin NK2 receptor subtypes in the rat. Eur J Pharmacol. 1998 Jul 3;352(1):103-9. [3]. Stephen D Tichenor, et al. Excitatory motor innervation in the canine rectoanal region: role of changing receptor populations. Br J Pharmacol. 2002 Dec;137(8):1321-9.

Density	1.282 g/cm3
Boiling Point	1310.4ºC at 760 mmHg
Molecular Formula	C₄₉H₆₁N₉O₈
Molecular Weight	904.06400
Flash Point	746.3ºC
Exact Mass	903.46400
PSA	245.00000
LogP	4.91880
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.617
Storage condition	-20°C

GR 94800 TFA MSDS(Chinese)

Chlor-essigsaeure-phenylester

Acetic acid,chloro-,phenyl este

chloro-aceticaciphenylester

chloroacetic acid phenyl ester

Phenyl-chloracetat

Chloracetoxy-benzol

Acetic acid,chloro-,phenyl ester

Phenyl-CO-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2

Phenylchloroacetate

PhCO-Ala-Ala-D-Trp-Phe-D-Pro-Pro-NleNH2

Phenyl cholroacetate

DC Chemicals Limited
China
Product Name: GR 94800
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: GR 94800
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

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