GR 55562 dihydrochloride
Modify Date: 2025-08-24 19:09:21
GR 55562 dihydrochloride structure
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Common Name | GR 55562 dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 159533-25-2 | Molecular Weight | 448.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H27Cl2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GR 55562 dihydrochlorideGR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1]. |
| Name | GR 55562 dihydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. GR 55562 can be used for the research of nerve disease[1]. |
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| Related Catalog | |
| In Vivo | GR 55562 (0.1-10 μg/side) 进入伏隔子区域不会引起cocaine杠杆响应[1]。 GR 55562 (0.1-10 μg/side)（伏核壳或核中）的未能调节cocaine（5 mg/kg）的辨别作用[1]。 GR 55562 (1 μg/side) 显着减弱了对cocaine的辨别作用[1]。 Animal Model: Male Wistar rats (280-300 g; n=50)[1]. Dosage: 0.1-10 μg/side Administration: Injected intracranially; At a volume of 0.2 µl/side Result: Did not evoke substitution for the drug with intra-accumbal shell infusion. Did not significantly affect the discriminative stimulus effects produced by 5 mg/kg of cocaine. GR 55562 (1 µg/side) attenuated the enhancement of cocaine discrimination evoked by a combination of intra-accumbal core CP 93129 (1 µg/side) and systemic cocaine (1.25 mg/ kg or 2.5 mg/kg). |
| References |
| Molecular Formula | C23H27Cl2N3O2 |
|---|---|
| Molecular Weight | 448.39 |
| Exact Mass | 447.148041 |
| 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(pyridin-4-yl)phenyl]benzamide dihydrochloride |
| 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride |
| Benzamide, 3-[3-(dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]-, hydrochloride (1:2) |
| MFCD06201848 |
| MFCD01861177 |