Propargyl-PEG7-alcohol

Modify Date: 2024-01-09 17:04:13

Propargyl-PEG7-alcohol Structure
Propargyl-PEG7-alcohol structure
Common Name Propargyl-PEG7-alcohol
CAS Number 1422023-54-8 Molecular Weight 364.431
Density 1.1±0.1 g/cm3 Boiling Point 447.2±40.0 °C at 760 mmHg
Molecular Formula C17H32O8 Melting Point N/A
MSDS N/A Flash Point 224.2±27.3 °C

 Use of Propargyl-PEG7-alcohol


Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG8-alcohol
Synonym More Synonyms

 Propargyl-PEG7-alcohol Biological Activity

Description Propargyl-PEG7-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 447.2±40.0 °C at 760 mmHg
Molecular Formula C17H32O8
Molecular Weight 364.431
Flash Point 224.2±27.3 °C
Exact Mass 364.209717
LogP -2.40
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.464
Storage condition 2-8°C

 Synonyms

3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol
MFCD28950752