Propargyl-PEG7-Boc

Modify Date: 2024-01-23 15:46:39

Propargyl-PEG7-Boc Structure
Propargyl-PEG7-Boc structure
Common Name Propargyl-PEG7-Boc
CAS Number 1818294-29-9 Molecular Weight 448.548
Density 1.1±0.1 g/cm3 Boiling Point 494.3±40.0 °C at 760 mmHg
Molecular Formula C22H40O9 Melting Point N/A
MSDS N/A Flash Point 207.8±27.4 °C

 Use of Propargyl-PEG7-Boc


Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG7-t-butyl ester
Synonym More Synonyms

 Propargyl-PEG7-Boc Biological Activity

Description Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 494.3±40.0 °C at 760 mmHg
Molecular Formula C22H40O9
Molecular Weight 448.548
Flash Point 207.8±27.4 °C
Exact Mass 448.267242
LogP -0.18
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.459

 Synonyms

2-Methyl-2-propanyl 4,7,10,13,16,19,22-heptaoxapentacos-24-yn-1-oate
4,7,10,13,16,19,22-Heptaoxapentacos-24-yn-1-oic acid, 1,1-dimethylethyl ester
MFCD22683299
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