Seclidemstat
Modify Date: 2024-01-08 14:33:14
Seclidemstat structure
|
Common Name | Seclidemstat | ||
|---|---|---|---|---|
| CAS Number | 1423715-37-0 | Molecular Weight | 450.939 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H23ClN4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SeclidemstatSeclidemstat (SP-2577) is a potent LSD1 inhibitor, with a mean IC50 of 127 nM. |
| Name | Seclidemstat |
|---|---|
| Synonym | More Synonyms |
| Description | Seclidemstat (SP-2577) is a potent LSD1 inhibitor, with a mean IC50 of 127 nM. |
|---|---|
| Related Catalog | |
| Target |
IC50: 127 nM (LSD1)[1] |
| In Vivo | Seclidemstat (Compound 2577) reduces tumor volume at 40, 80 mg/kg by i.p. and also shows such effect at 80 mg/kg via p.o. dosing. |
| References |
[1]. SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS. WO/2017/004519 A1 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H23ClN4O4S |
| Molecular Weight | 450.939 |
| Exact Mass | 450.112854 |
| LogP | 4.07 |
| Index of Refraction | 1.645 |
| Storage condition | 2-8℃ |
| N'-[(1E)-1-(5-Chloro-2-hydroxyphenyl)ethylidene]-3-[(4-methyl-1-piperazinyl)sulfonyl]benzohydrazide |
| TYH386V3WJ |
| Benzoic acid, 3-[(4-methyl-1-piperazinyl)sulfonyl]-, 2-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide |