FR 139317

Modify Date: 2024-01-13 18:53:20

FR 139317 Structure
FR 139317 structure
Common Name FR 139317
CAS Number 142375-60-8 Molecular Weight 604.74000
Density 1.27 g/cm3 Boiling Point 943.9ºC at 760 mmHg
Molecular Formula C33H44N6O5 Melting Point N/A
MSDS N/A Flash Point 524.6ºC

 Use of FR 139317


FR 139317 is a highly potent and selective antagonist of ETA endothelin receptor, with Ki values of 1 nM and 7.3 μM for ETA and ETB subtypes, respectively.

 Names

Name (R)2-[(R)-2[(S)-2[[1-(hexahydro-1H-azepinyl)] carbonyl] amino-4-methylpentanoyl] amino-3-[3-(1-methyl-1H-indolyl)] propionyl] amino-3-(2-pyridyl) propionic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.27 g/cm3
Boiling Point 943.9ºC at 760 mmHg
Molecular Formula C33H44N6O5
Molecular Weight 604.74000
Flash Point 524.6ºC
Exact Mass 604.33700
PSA 145.66000
LogP 4.52360
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.63

 Synonyms

4-BMA
1-Bma Or 4-Bma
Side chain for iMipe
1-BMA
B-METHYLAZETIDIN-2-ONE
SS-METHYLAZETIDIN-2-ONE
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