hGGPPS-IN-1

Modify Date: 2024-01-08 10:57:14

hGGPPS-IN-1 Structure
hGGPPS-IN-1 structure
Common Name hGGPPS-IN-1
CAS Number 1429012-38-3 Molecular Weight 401.27
Density N/A Boiling Point N/A
Molecular Formula C13H13N3O6P2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of hGGPPS-IN-1


hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo[1].

 Names

Name hGGPPS-IN-1

 hGGPPS-IN-1 Biological Activity

Description hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selective apoptosis of multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo[1].
Related Catalog
References

[1]. Lee HF, et al. Synthesis and Evaluation of Structurally Diverse C-2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase. J Med Chem. 2022;65(3):2471-2496.

 Chemical & Physical Properties

Molecular Formula C13H13N3O6P2S
Molecular Weight 401.27
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.