BMS-962212
Modify Date: 2025-08-27 11:23:45
BMS-962212 structure
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Common Name | BMS-962212 | ||
|---|---|---|---|---|
| CAS Number | 1430114-34-3 | Molecular Weight | 659.07 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H28ClFN8O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS-962212BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1]. |
| Name | BMS-962212 |
|---|
| Description | BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C32H28ClFN8O5 |
|---|---|
| Molecular Weight | 659.07 |
| InChIKey | WYFCZWSWFGJODV-MIANJLSGSA-N |
| SMILES | CN1CCN(c2cccc3c2CCN(C(=O)C=Cc2c(-n4cnnn4)ccc(Cl)c2F)C3C(=O)Nc2ccc(C(=O)O)cc2)C(=O)C1 |
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Name: Lipophilicity, log D of the compound by HPLC method
Source: ChEMBL
Target: N/A
External Id: CHEMBL4032069
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Name: Acid dissociation constant, pKa of the compound
Source: ChEMBL
Target: N/A
External Id: CHEMBL4032070
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Name: Genotoxicity in Salmonella typhi by Ames test
Source: ChEMBL
Target: Salmonella enterica subsp. enterica serovar Typhi
External Id: CHEMBL4032068
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Name: Fraction unbound in cynomolgus monkey serum
Source: ChEMBL
Target: N/A
External Id: CHEMBL4032065
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Name: Chemical stability of the compound in phosphate buffer at pH 6.5 at 25 degC after 90 ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4032077
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Name: Terminal half life in healthy human following administration of 2 hrs and 5 day conti...
Source: ChEMBL
Target: Homo sapiens
External Id: CHEMBL4199295
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Name: Chemical stability of the compound in phosphate buffer at pH 7.4 at 25 degC after 90 ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4032078
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