GDC-0853

Modify Date: 2024-01-03 14:29:23

GDC-0853 Structure
GDC-0853 structure
Common Name GDC-0853
CAS Number 1434048-34-6 Molecular Weight 664.797
Density 1.4±0.1 g/cm3 Boiling Point 936.3±65.0 °C at 760 mmHg
Molecular Formula C37H44N8O4 Melting Point N/A
MSDS N/A Flash Point 520.0±34.3 °C

 Use of GDC-0853


GDC-0853 is a potent, selective, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with a Ki of 0.91 nM.

 Names

Name GDC0853
Synonym More Synonyms

 GDC-0853 Biological Activity

Description GDC-0853 is a potent, selective, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with a Ki of 0.91 nM.
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 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 936.3±65.0 °C at 760 mmHg
Molecular Formula C37H44N8O4
Molecular Weight 664.797
Flash Point 520.0±34.3 °C
Exact Mass 664.348572
LogP 1.59
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.725

 Synonyms

2-[3'-(Hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(3-oxetanyl)-1-piperazinyl]-2-pyridinyl}amino)-6-oxo-1,6-dihydro-3,4'-bipyridin-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one
2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, 2-[1,6-dihydro-3'-(hydroxymethyl)-1-methyl-5-[[5-[(2S)-2-methyl-4-(3-oxetanyl)-1-piperazinyl]-2-pyridinyl]amino]-6-oxo[3,4'-bipyridin]-2'-yl]-3,4,7,8-tetrahydro-7,7-dimethyl-
GDC-0853
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Price: $139/10mM*1mLinDMSO

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