Licochalcone D

Modify Date: 2024-01-08 18:40:51

Licochalcone D Structure
Licochalcone D structure
 Common Name Licochalcone D
CAS Number 144506-15-0 Molecular Weight 354.39600
Density N/A Boiling Point N/A
Molecular Formula C21H22O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Licochalcone D


Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2].

 Names

Name (E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Synonym More Synonyms

 Licochalcone D Biological Activity

Description Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2].
Related Catalog
Target

p65

References

[1]. Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507.

[2]. Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39(5):2160-2170.

 Chemical & Physical Properties

Molecular Formula C21H22O5
Molecular Weight 354.39600
Exact Mass 354.14700
PSA 86.99000
LogP 4.21680
Storage condition 2-8℃

 Synonyms

UNII-3P0SH94V09
Licochalcone D
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Chemsrc provides Licochalcone D(CAS#:144506-15-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Licochalcone D are included as well.>> amp version: Licochalcone D

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