Licochalcone D

Modify Date: 2024-01-08 18:40:51

Licochalcone D structure	Common Name	Licochalcone D
	CAS Number	144506-15-0	Molecular Weight	354.39600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Licochalcone D

Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2].

Name	(E)-3-(3,4-dihydroxy-2-methoxyphenyl)-1-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
Synonym	More Synonyms

Description	Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza inflate, is a potent inhibitor of NF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	p65
References	[1]. Furusawa J, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507. [2]. Si L, et al. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncol Rep. 2018 May;39(5):2160-2170.

Molecular Formula	C₂₁H₂₂O₅
Molecular Weight	354.39600
Exact Mass	354.14700
PSA	86.99000
LogP	4.21680
Storage condition	2-8℃

UNII-3P0SH94V09

Licochalcone D

Licochalcone D

Use of Licochalcone D

Names

Licochalcone D Biological Activity

Chemical & Physical Properties

Synonyms