MRS 2179 tetrasodium
Modify Date: 2024-01-08 09:23:55
MRS 2179 tetrasodium structure
|
Common Name | MRS 2179 tetrasodium | ||
|---|---|---|---|---|
| CAS Number | 1454889-37-2 | Molecular Weight | 513.156 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H13N5O9P2Na4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MRS 2179 tetrasodiumMRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM; displays no appreciable activity at P2Y2, P2Y4, or P2Y6 receptors (>30 uM); inhibits ADP-induced platelet shape change, aggregation and Ca2+ rise but has no effect on ADP-induced inhibition of adenylyl cyclase; decreases platelet count in mice. |
| Name | Tetrasodium 9-(2-deoxy-3,5-di-O-phosphonato-α-D-erythro-pentofuranosyl)-N-methyl-9H-purin-6-amine |
|---|---|
| Synonym | More Synonyms |
| Description | MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM; displays no appreciable activity at P2Y2, P2Y4, or P2Y6 receptors (>30 uM); inhibits ADP-induced platelet shape change, aggregation and Ca2+ rise but has no effect on ADP-induced inhibition of adenylyl cyclase; decreases platelet count in mice. |
|---|---|
| References | References 1. Moro S, et al. J Med Chem. 1998 Apr 23;41(9):1456-66. 2. Baurand A, et al. Eur J Pharmacol. 2001 Feb 2;412(3):213-21. 3. Léon C, et al. Circulation. 2001 Feb 6;103(5):718-23. View Related Products by Target P2Y Receptor |
| Molecular Formula | C11H13N5O9P2Na4 |
|---|---|
| Molecular Weight | 513.156 |
| Exact Mass | 512.977905 |
| Tetrasodium 9-(2-deoxy-3,5-di-O-phosphonato-α-D-erythro-pentofuranosyl)-N-methyl-9H-purin-6-amine |
| 9H-Purin-6-amine, 9-(2-deoxy-3,5-di-O-phosphono-α-D-erythro-pentofuranosyl)-N-methyl-, sodium salt (1:4) |