JTV-519 free base
Modify Date: 2025-08-24 08:47:42
JTV-519 free base structure
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Common Name | JTV-519 free base | ||
|---|---|---|---|---|
| CAS Number | 145903-06-6 | Molecular Weight | 424.59900 | |
| Density | 1.153 g/cm3 | Boiling Point | 615.133ºC at 760 mmHg | |
| Molecular Formula | C25H32N2O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 325.821ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of JTV-519 free baseJTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1]. |
| Name | 3-(4-benzylpiperidin-1-yl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.153 g/cm3 |
|---|---|
| Boiling Point | 615.133ºC at 760 mmHg |
| Molecular Formula | C25H32N2O2S |
| Molecular Weight | 424.59900 |
| Flash Point | 325.821ºC |
| Exact Mass | 424.21800 |
| PSA | 58.08000 |
| LogP | 4.35010 |
|
~%
JTV-519 free base CAS#:145903-06-6 |
| Literature: Marks, Andrew R.; Landry, Donald W.; Deng, Shi Xian; Cheng, Zhen Zhuang Patent: US2005/215540 A1, 2005 ; Location in patent: Page/Page column 37 ; |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| K201 free base |
| JTV-519 hemifumarate |
| 4-[3-(4-Benzylpiperidin-1-yl)propionyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine |
| K201 |
| UNII-EBY0ENK2GQ |
| K21 |
| JTV 519 |