JTV-519 hemifumarate

Modify Date: 2023-01-14 11:50:34

JTV-519 hemifumarate Structure
JTV-519 hemifumarate structure
Common Name JTV-519 hemifumarate
CAS Number 1435938-25-2 Molecular Weight 482.64
Density N/A Boiling Point N/A
Molecular Formula C25H32N2O2S.1/2C4H4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JTV-519 hemifumarate


JTV-519 hemifumarate (K201 hemifumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].

 Names

Name JTV-519 hemifumarate

 JTV-519 hemifumarate Biological Activity

Description JTV-519 hemifumarate (K201 hemifumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].
References

[1]. Darcy YL, et al. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.

 Chemical & Physical Properties

Molecular Formula C25H32N2O2S.1/2C4H4O4
Molecular Weight 482.64