calcein
Modify Date: 2025-08-25 15:33:27
calcein structure
|
Common Name | calcein | ||
|---|---|---|---|---|
| CAS Number | 1461-15-0 | Molecular Weight | 622.533 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 952.7±65.0 °C at 760 mmHg | |
| Molecular Formula | C30H26N2O13 | Melting Point | 200 °C | |
| MSDS | Chinese | Flash Point | 530.0±34.3 °C | |
Use of calceinCalcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. |
| Name | calcein |
|---|---|
| Synonym | More Synonyms |
| Description | Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. |
|---|---|
| Related Catalog | |
| In Vitro | Calcein accumulates intracellularly in coelomocytes incubated in coelomic fluid or ISO-EDTA. Coelomocytes incubated in CF show an increase in the calcein fluorescence intensity compared to the control. |
| Cell Assay | Coelomocytes suspensions (ISO and CF) are separately incubated with calcein-AM (excitation and emission wavelength: 496 nm and 516 nm, respectively) at a final concentration of 200 nM, during 30 min, at 26°C. Calcein-AM is a nonfluorescent ABC transporter substrate whose intracellular accumulation is inversely proportional to ABC transporter activity. Intracellular esterases convert calcein-AM into the fluorescent dye calcein, which is not an ABC transporter substrate, thereby accumulating the dye inside the cell. Therefore, a high fluorescence signal indicates low ABC transporter activity whereas a low fluorescence signal indicates high activity. The fluorescence of samples is measured by flow cytometer. The experiment is repeated six times in duplicates. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 952.7±65.0 °C at 760 mmHg |
| Melting Point | 200 °C |
| Molecular Formula | C30H26N2O13 |
| Molecular Weight | 622.533 |
| Flash Point | 530.0±34.3 °C |
| Exact Mass | 622.143494 |
| PSA | 231.67000 |
| LogP | 1.56 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.775 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility | insoluble |
| Hazard Codes | Xn:Harmful; |
|---|---|
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S22-S24/25-S36/37/39-S26 |
| WGK Germany | 3 |
| HS Code | 32041900 |
| HS Code | 32041900 |
|---|
| Fluorescein-bis(methyliminodiacetic acid) |
| Oftasceinum |
| Fluorexon |
| EINECS 215-957-1 |
| Fluorescein complexon |
| 2-[[7'-[[bis(carboxymethyl)amino]methyl]-3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-2'-yl]methyl-(carboxymethyl)amino]acetic acid |
| 2,2',2'',2'''-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methylenenitrilo)]tetraacetic acid |
| Bis[N,N−bis(carboxymethyl)aminomethyl]fluorescein |
| Oftasceina |
| calcein |
| 2,2',2'',2'''-[(3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-2',7'-diyl)bis(methanediylnitrilo)]tetraacetic acid |
| Oftasceine |
| MFCD00005049 |
| oftasceinum [INN_la] |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: calcein
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- China
- Product Name: Calcein
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- Zhongshan Xingrui Chemical Co. , Ltd.
- China
- Product Name: calcein
- Price: ￥Inquiry/25kg
- Purity: 99.0%
- Delivery: Inquiry
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