YM 511

Modify Date: 2024-01-06 17:35:08

YM 511 Structure
YM 511 structure
Common Name YM 511
CAS Number 148869-05-0 Molecular Weight 354.20400
Density 1.44g/cm3 Boiling Point 551.9ºC at 760 mmHg
Molecular Formula C16H12BrN5 Melting Point N/A
MSDS N/A Flash Point 287.6ºC

 Use of YM 511


YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones[1].

 Names

Name 4-[(4-bromophenyl)methyl-(1,2,4-triazol-4-yl)amino]benzonitrile
Synonym More Synonyms

 YM 511 Biological Activity

Description YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones[1].
Related Catalog
References

[1]. M Kudoh, et al. The potent and selective inhibition of estrogen production by non-steroidal aromatase inhibitor, YM511. J Steroid Biochem Mol Biol. 1995 Sep;54(5-6):265-71.

 Chemical & Physical Properties

Density 1.44g/cm3
Boiling Point 551.9ºC at 760 mmHg
Molecular Formula C16H12BrN5
Molecular Weight 354.20400
Flash Point 287.6ºC
Exact Mass 353.02800
PSA 57.74000
LogP 3.38218
Vapour Pressure 3.18E-12mmHg at 25°C
Index of Refraction 1.675

 Synonyms

ym-511
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