Menthol

Modify Date: 2024-01-03 13:08:16

Menthol Structure
Menthol structure
 Common Name Menthol
CAS Number 1490-04-6 Molecular Weight 156.265
Density 0.9±0.1 g/cm3 Boiling Point 215.4±8.0 °C at 760 mmHg
Molecular Formula C10H20O Melting Point 34-36 ℃(lit.)
MSDS Chinese USA Flash Point 93.3±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07		 Signal Word Danger

 Use of Menthol


Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes[1].

 Names

Name 2-Isopropyl-5-methylcyclohexanol
Synonym More Synonyms

 Menthol Biological Activity

Description Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes[1].
Related Catalog
References

[1]. NicolettaGaleotti, et al. Menthol: a natural analgesic compound. Neuroscience Letters. 2002 Apr.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 215.4±8.0 °C at 760 mmHg
Melting Point 34-36 ℃(lit.)
Molecular Formula C10H20O
Molecular Weight 156.265
Flash Point 93.3±0.0 °C
Exact Mass 156.151413
PSA 20.23000
LogP 3.20
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.457
Stability Stable. Combustible. Incompatible with strong oxidizing agents.

 MSDS

Name: DL-Menthol 99% Material Safety Data Sheet
Synonym: p-Menthan-3-o
CAS: 1490-04-6
Section 1 - Chemical Product MSDS Name:DL-Menthol 99% Material Safety Data Sheet
Synonym:p-Menthan-3-o
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1490-04-6 DL-Menthol 99 216-074-4
Hazard Symbols: XI
Risk Phrases: 36/37/38
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water fog, dry chemical, carbon dioxide, or regular foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1490-04-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 28.00 - 30.00 deg C
Autoignition Temperature: Not available.
Flash Point: 93 deg C ( 199.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble in alcohol, chloroform and ether
Specific Gravity/Density: .8900g/cm3
Molecular Formula: C10H20O
Molecular Weight: 156.27
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1490-04-6: GW0554000 LD50/LC50:
Not available.
Carcinogenicity:
DL-Menthol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 1490-04-6: 1
Canada
CAS# 1490-04-6 is listed on Canada's DSL List.
CAS# 1490-04-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1490-04-6 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GW0554000
CHEMICAL NAME :
Cyclohexanol, 5-methyl-2-(1-methylethyl)-
CAS REGISTRY NUMBER :
1490-04-6
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H20-O

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H315-H318-H335
Precautionary Statements P280-P305 + P351 + P338 + P310
Hazard Codes Xn,Xi
Risk Phrases 37/38-41-48/20/22-40-22
Safety Phrases 36/37/39-36-26
RIDADR UN 1888 6.1/PG 3
WGK Germany 2
RTECS OT0525000

 Articles54

More Articles
Carbopol 934, 940 and Ultrez 10 as viscosity modifiers of palm olein esters based nano-scaled emulsion containing ibuprofen.

Pak. J. Pharm. Sci. 26(1) , 75-83, (2013)

Micro-emulsions and sometimes nano-emulsions are well known candidates to deliver drugs locally. However, the poor rheological properties are marginally affecting their acceptance pharmaceutically. Th...

Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site.

Mol. Pharmacol. 87(1) , 87-95, (2015)

In common with other members of the Cys-loop family of pentameric ligand-gated ion channels, 5-hydroxytryptamine type 3 receptors (5-HT3Rs) are activated by the binding of a neurotransmitter to an ext...

Corneal sensory nerve activity in an experimental model of UV keratitis.

Invest. Ophthalmol. Vis. Sci. 55(6) , 3403-12, (2014)

To produce in guinea pigs a UV-induced keratitis, to analyze the effects of this pathology on corneal nerve activity.In anesthetized animals, one eye was exposed to 254 nm UV-C radiation (500-1000 mJ/...

 Synonyms

(1R,2S,5R)-(−)-Menthol
levo-menthol
EINECS 216-074-4
(-)-(1R,3R,4S)-Menthol
(−)-menthol
(-)-trans-p-Methan-cis-3-ol
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol
Levomenthol
L-Menthol
(-)-(1R,2S,5R)-Menthol
(-)-MENTHYL ALCOHOL
(1R)-(-)-Menthol
(R)-(-)-Menthol
DL-Menthol
(1R,2S,5R)-5-methyl-2-propan-2-yl-cyclohexan-1-ol
[1R-(1a,2b,5a)]-5-Methyl-2-(1-methylethyl)cyclohexanol
(-)-p-Menthan-3-ol
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-
(-)-Menthol
UNII:YS08XHA860
Menthol, l-
Menthol
(1R,2S,5R)-(-)-Menthol
MFCD00001484
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Menthol suppliers

Price: ￥325/100g

Reference only. check more Menthol price

Related Compounds: More...
Menthol
89-78-1
menthol
15356-70-4
Menthol
15356-60-2
Menthol
2216-51-5
menthol
20752-33-4
L-MENTHOL
4835-96-5
Menthol-d4
1217765-02-0
Neomenthol
3623-51-6
NEOMENTHOL
491-01-0
2-Chloro-3-(pyrrolidin-3-yloxy)pyrazine
1707393-84-7
3-[1-(4-Fluoro-phenyl)-ethoxy]-pyrrolidine
1710471-64-9
1-(Piperazin-1-yl)cyclopropane-1-carboxamide
1699434-88-2
2-(3-Chloro-4-methylthiophen-2-yl)pyrrolidine
1270406-31-9
(S)-2-Amino-3-(2-chloro-3-fluorophenyl)propanoic acid
1269993-67-0
1,1,1-Trifluoro-N-(4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)methanesulfonamide
1604706-73-1
4-Chloro-6-(5-fluoropyridin-3-yl)pyrimidine
1492369-44-4
(S)-6-((1-Methoxy-1-oxopropan-2-yl)amino)-6-oxohexanoic acid
1309009-95-7
2-Chloro-6-(2-fluorophenyl)pyrazine
1416916-44-3
1-Chloro-2-methyl-3-(propan-2-yloxy)propane
854258-38-1
Chemsrc provides Menthol(CAS#:1490-04-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Menthol are included as well.>> amp version: Menthol

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved