(S)-WAY 100135

Modify Date: 2024-01-01 18:46:36

(S)-WAY 100135 Structure
(S)-WAY 100135 structure
Common Name (S)-WAY 100135
CAS Number 149007-54-5 Molecular Weight 468.46
Density N/A Boiling Point N/A
Molecular Formula C24H35Cl2N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-WAY 100135


(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].

 Names

Name (2S)-3-[4-(2-Methoxyphenyl)-1-piperazinyl]-N-(2-methyl-2-propanyl )-2-phenylpropanamide dihydrochloride

 (S)-WAY 100135 Biological Activity

Description (S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].
Related Catalog
References

[1]. Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.  

 Chemical & Physical Properties

Molecular Formula C24H35Cl2N3O2
Molecular Weight 468.46
Exact Mass 467.21100
PSA 48.30000
LogP 5.96290
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