N,N-bis(2-hydroxyethyl)glycine

Modify Date: 2025-08-25 06:31:35

N,N-bis(2-hydroxyethyl)glycine structure	Common Name	N,N-bis(2-hydroxyethyl)glycine
	CAS Number	150-25-4	Molecular Weight	163.17
	Density	1.3±0.1 g/cm3	Boiling Point	388.5±27.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₃NO₄	Melting Point	190 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	188.8±23.7 °C

Use of N,N-bis(2-hydroxyethyl)glycine

Bicine is a useful buffer in the range of physiological interest. Bicine is a derivative of the simple amino acid glycine[1].

Name	N,N-bis(2-hydroxyethyl)glycine
Synonym	More Synonyms

Description	Bicine is a useful buffer in the range of physiological interest. Bicine is a derivative of the simple amino acid glycine[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Taha M, et al. Mixed-ligand complex formation equilibria of cobalt (II), nickel (II), and copper (II) with N, N-bis (2-hydroxyethyl) glycine (bicine) and some amino acids[J]. Journal of Chemical & Engineering Data, 2005, 50(1): 157-163.

Density	1.3±0.1 g/cm3
Boiling Point	388.5±27.0 °C at 760 mmHg
Melting Point	190 °C (dec.)(lit.)
Molecular Formula	C₆H₁₃NO₄
Molecular Weight	163.17
Flash Point	188.8±23.7 °C
Exact Mass	163.084457
PSA	81.00000
LogP	-0.47
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.526
InChIKey	FSVCELGFZIQNCK-UHFFFAOYSA-N
SMILES	O=C(O)CN(CCO)CCO
Storage condition	2-8°C
Water Solubility	soluble

N,N-bis(2-hydroxyethyl)glycine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9700000

CHEMICAL NAME :: Glycine, N,N-dihydroxyethyl-

CAS REGISTRY NUMBER :: 150-25-4

BEILSTEIN REFERENCE NO. :: 1769362

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H13-N-O4

MOLECULAR WEIGHT :: 163.20

WISWESSER LINE NOTATION :: QV1N2Q2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1540 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1- 1953- Volume(issue)/page/year: 10,391,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9723 No. of Facilities: 130 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 1828 (estimated) No. of Female Employees: 1552 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MB9700000
HS Code	29225000

Precursor 8
CAS#:96-32-2 Methyl bromoacetate CAS#:111-42-2 dea CAS#:79-11-8 Chloroacetic acid CAS#:98486-41-0 2-[bis(2-chloro...
CAS#:64-69-7 Iodoacetic acid CAS#:3926-62-3 Sodium chloroacetate CAS#:50-00-0 Formaldehyde CAS#:151-50-8 POTASSIUM CYANIDE
DownStream 3
CAS#:53883-47-9 5-phenyl-4,6,11... CAS#:53883-49-1 5-methyl-4,6,11... CAS#:53883-57-1 5-ethenyl-4,6,1...

HS Code	29225000

Endothelial transcriptome in response to pharmacological methyltransferase inhibition.

ChemMedChem 9(8) , 1755-62, (2014)

The enzymatic activities of protein methyltransferases serve to write covalent modifications on histone and non-histone proteins in the control of gene transcription. Here, we describe gene expression...

A Comprehensive Immunoreceptor Phosphotyrosine-based Signaling Network Revealed by Reciprocal Protein-Peptide Array Screening.

Mol. Cell. Proteomics 14 , 1846-58, (2015)

Cells of the immune system communicate with their environment through immunoreceptors. These receptors often harbor intracellular tyrosine residues, which, when phosphorylated upon receptor activation...

Solubilization of gliadins for use as a source of nitrogen in the selection of bacteria with gliadinase activity.

Food Chem. 168 , 439-44, (2014)

For patients with celiac disease, gliadin detoxification via the use of gliadinases may provide an alternative to a gluten-free diet. A culture medium, in which gliadins were the sole source of nitrog...

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262

Name: qHTS assay for inhibitors of human lactate dehydrogenase
Source: NCGC
Target: N/A
External Id: LDHA

Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315

Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-FF

Name: Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
Source: NCGC
External Id: stopgo-p2-SytraCBC-dual-Ren

Name: Modulation of human Nur77 LBD transiently transfected in HEK293T cells at 100 to 200 ...
Source: ChEMBL
Target: Nuclear receptor subfamily 4immunitygroup A member 1
External Id: CHEMBL5392231

Name: MELAS cybrid survival enhancement under low glucose conditions
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1419

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Diethylolglycine

N,N-Bis(2-hydroxyethyl)glycine,BICINE,PEG Grid Screening

Di(hydroxyethyl)glycine

N,N-Dihydroxyethyl glycine

bicine buffer

Bis(2-Hydroxyethyl)glycine

Bicine

BICINE[N,N-Di(2-hydroxyethyl)glycine]

EINECS 205-755-1

Bicene

N,N-Bis(b-hydroxyethyl)glycine

N,N-Di(2-hydroxyethyl)glycine

Diethanolglycine

2-[bis(2-hydroxyethyl)amino]acetic acid

2-HxG

2-(bis(2-hydroxyethyl)amino)acetic acid

N,N-Bis(β-hydroxyethyl)glycine

MFCD00004295

(Bis(2-hydroxyethyl)amino)acetic Acid

N,N-dihydroxyethylglycine

N,N-Bis(2-hydroxyethyl)aminoacetic acid

N,N-Bis(hydroxyethyl)glycine

N,N-Bis(2-hydroxyethyl)glycine

N,N-Di(2-hydroxyethyl)glycine [Good's buffer component

N,N-Di(hydroxyethyl)aminoacetic Acid

Diethanol glycine

N,N-Bis(2-hydroxyethyl)glycine (Bicine)

Dihydroxyethylglycine

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China
Product Name: N,N-bis(2-hydroxyethyl)glycine
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Bicine--
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: N,N-bis(2-hydroxyethyl)glycine
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Price: ￥600/25 mg

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N,N-bis(2-hydroxyethyl)glycine

Use of N,N-bis(2-hydroxyethyl)glycine

Names