Phytol

Modify Date: 2024-01-02 09:57:26

Phytol Structure
Phytol structure
Common Name Phytol
CAS Number 150-86-7 Molecular Weight 296.531
Density 0.8±0.1 g/cm3 Boiling Point 335.5±0.0 °C at 760 mmHg
Molecular Formula C20H40O Melting Point N/A
MSDS USA Flash Point 157.5±8.9 °C

 Use of Phytol


Phytol ((E)​-​Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, possesses promising antischistosomal properties. Phytol has antinociceptive and antioxidant activitiesas well as anti-inflammatory and antiallergic effects. Phytol has antimicrobial activity against Mycobacterium tuberculosis and Staphylococcus aureus[1].

 Names

Name phytol
Synonym More Synonyms

 Phytol Biological Activity

Description Phytol ((E)​-​Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, possesses promising antischistosomal properties. Phytol has antinociceptive and antioxidant activitiesas well as anti-inflammatory and antiallergic effects. Phytol has antimicrobial activity against Mycobacterium tuberculosis and Staphylococcus aureus[1].
Related Catalog
References

[1]. de Moraes J, et al. Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical diseaseSchistosomiasis mansoni. PLoS Negl Trop Dis. 2014 Jan 2;8(1):e2617.

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 335.5±0.0 °C at 760 mmHg
Molecular Formula C20H40O
Molecular Weight 296.531
Flash Point 157.5±8.9 °C
Exact Mass 296.307922
PSA 20.23000
LogP 8.66
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.460
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TJ3490000
CHEMICAL NAME :
Phytol
CAS REGISTRY NUMBER :
150-86-7
BEILSTEIN REFERENCE NO. :
1726098
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H40-O
MOLECULAR WEIGHT :
296.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,811,1982 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,811,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,811,1982

 Safety Information

Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S37/39-S26
RTECS TJ3490000
HS Code 2905290000

 Synthetic Route

 Customs

HS Code 2905290000
Summary 2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

(2E,7R,11R)-3,7,11,15- tetramethyl-2-hexadecen-1-ol
(2E)(7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol
Phytol
3,7,11,15-Tetramethylhexadec-2-en-1-ol
(2E,7R,11R)-3,7,11,15-Tetramethylhexadec-2-en-1-ol
4-01-00-02208 (Beilstein Handbook Reference)
2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-, (2E,7R,11R)-
(2E,7R,11R)-3,7,11,15-Tetramethyl-2-hexadecen-1-ol
(7R,11R,2E)-Phytol
trans-phytol
EINECS 205-776-6
MFCD00151280
(E)-Phytol
Phytol, E-
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