Beta-Tocopherol
Beta-Tocopherol structure
|
Common Name | Beta-Tocopherol | ||
|---|---|---|---|---|
| CAS Number | 148-03-8 | Molecular Weight | 416.680 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 516.3±49.0 °C at 760 mmHg | |
| Molecular Formula | C28H48O2 | Melting Point | <25℃ | |
| MSDS | N/A | Flash Point | 204.7±24.1 °C | |
| Symbol |
GHS02, GHS07, GHS08, GHS09 |
Signal Word | Danger | |
Use of Beta-Tocopherol(rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1]. |
Summary: 3,4-Dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol, also known as 5,8-dimethyl-tocopherol/vitamin E, is the chemical name β-tocopherol, with CAS number 148-03-8, and molecular formula C28H48O2, molecular weight 416.680. It appears as an oily substance with a melting point below 25℃, a boiling point of 516.3±49.0 °C at 760 mmHg, and a density of 0.9±0.1 g/cm3. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | β-tocopherol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | (rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 516.3±49.0 °C at 760 mmHg |
| Melting Point | <25℃ |
| Molecular Formula | C28H48O2 |
| Molecular Weight | 416.680 |
| Flash Point | 204.7±24.1 °C |
| Exact Mass | 416.365417 |
| PSA | 29.46000 |
| LogP | 11.44 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.495 |
| InChIKey | WGVKWNUPNGFDFJ-DQCZWYHMSA-N |
| SMILES | Cc1cc(O)c(C)c2c1OC(C)(CCCC(C)CCCC(C)CCCC(C)C)CC2 |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS02, GHS07, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H304-H315-H336-H361f-H373-H411 |
| Precautionary Statements | P201-P210-P273-P301 + P310-P308 + P313-P331 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | F,Xn,N |
| Risk Phrases | 11-38-48/20-51/53-62 |
| Safety Phrases | 36/37-61-62 |
| RIDADR | UN1208 3/PG 2 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Beta-Tocopherol CAS#:148-03-8 |
| Literature: DSM IP Assets B.V. Patent: EP2522647 A1, 2012 ; Location in patent: Page/Page column 15 ; |
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Beta-Tocopherol CAS#:148-03-8 |
| Literature: Emerson; Smith Journal of the American Chemical Society, 1940 , vol. 62, p. 1869,1871 Full Text Show Details Jacob et al. Journal of the Chemical Society, 1939 , p. 542,544 Full Text Show Details Hoffmann-La Roche Patent: CH214350 , 1939 ; |
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Beta-Tocopherol CAS#:148-03-8 |
| Literature: Karrer; Fritzsche Helvetica Chimica Acta, 1938 , vol. 21, p. 1234,1239 Full Text Show Details Karrer et al. Helvetica Chimica Acta, 1939 , vol. 22, p. 1139,1145 |
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Beta-Tocopherol CAS#:148-03-8 |
| Literature: Green et al. Journal of the Chemical Society, 1959 , p. 3362,3369 |
|
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Beta-Tocopherol CAS#:148-03-8 |
| Literature: Hoffmann-La Roche Patent: US2411967 , 1938 ; Full Text Show Details Hoffmann-La Roche Patent: DE731972 , 1938 ; DRP/DRBP Org.Chem. |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| beta-tocopherol |
| Cumotocopherol |
| p-Xylotocopherol |
| (2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol |
| Neotocopherol |
| β-tocopherol |
| (2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-6-chromanol |
| Tocopherol,rac-b |
| (2R)-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol |
| 5,8-DIMETHYLTOCOL |
| EINECS 205-708-5 |
| b-Tocopherol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of β-tocopherol? |
| A: LogP of β-tocopherol is 11.44. |
| Q: What is the polar surface area (PSA) of β-tocopherol? |
| A: Polar surface area (PSA) of β-tocopherol is 29.46000. |
| Q: What are the uses of β-tocopherol? |
| A: Main uses of β-tocopherol: (rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1]. |
| Q: What is the safety information for β-tocopherol? |
| A: Safety information for β-tocopherol: 36/37-61-62. |
| Q: What is the melting point of β-tocopherol? |
| A: Melting point of β-tocopherol is <25℃. |
| Q: What is the English name of β-tocopherol? |
| A: The English name of β-tocopherol is β-tocopherol. |
| Q: What is the boiling point of β-tocopherol? |
| A: Boiling point of β-tocopherol is 516.3±49.0 °C at 760 mmHg. |
| Q: What are the storage conditions for β-tocopherol? |
| A: Storage conditions for β-tocopherol: 2-8°C. |
| Q: What English synonyms does β-tocopherol have? |
| A: English synonyms of β-tocopherol: beta-tocopherol, Cumotocopherol, p-Xylotocopherol, (2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol, Neotocopherol, β-tocopherol, (2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-6-chromanol, Tocopherol,rac-b, (2R)-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol, 5,8-DIMETHYLTOCOL, EINECS 205-708-5, b-Tocopherol. |
| Q: What is the InChIKey of β-tocopherol? |
| A: InChIKey of β-tocopherol is WGVKWNUPNGFDFJ-DQCZWYHMSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |