CGP-53716

Modify Date: 2024-01-19 14:30:12

CGP-53716 Structure
CGP-53716 structure
Common Name CGP-53716
CAS Number 152459-94-4 Molecular Weight 381.43
Density N/A Boiling Point N/A
Molecular Formula C23H19N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CGP-53716


CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation [1].

 Names

Name N-(4-methyl-3(4-(pyridine-3-yl)pyrimidin-2-ylamino)phenyl)benzamide
Synonym More Synonyms

 CGP-53716 Biological Activity

Description CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation [1].
Related Catalog
References

[1]. Buchdunger E, et al. Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2558-62.  

 Chemical & Physical Properties

Molecular Formula C23H19N5O
Molecular Weight 381.43
Exact Mass 381.15900
PSA 79.80000
LogP 4.98890

 Synonyms

N-[4-methyl-3-(4-pyridin-3-ylpyrimidin-2-ylamino)phenyl]benzamide
N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
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