A 366

Modify Date: 2024-01-26 16:06:23

A 366 Structure
A 366 structure
Common Name A 366
CAS Number 1527503-11-2 Molecular Weight 329.43700
Density N/A Boiling Point N/A
Molecular Formula C19H27N3O2 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS09
GHS09
Signal Word Warning

 Use of A 366


A-366 is a potent histone methyltransferase G9a inhibitor with an IC50 of 3.3 nM.

 Names

Name a-366
Synonym More Synonyms

 A 366 Biological Activity

Description A-366 is a potent histone methyltransferase G9a inhibitor with an IC50 of 3.3 nM.
Related Catalog
References

[1]. Pappano WN, et al. The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.PLoS One. 2015 Jul 6;10(7):e0131716.

 Chemical & Physical Properties

Molecular Formula C19H27N3O2
Molecular Weight 329.43700
Exact Mass 329.21000
PSA 60.08000
LogP 3.05770
Storage condition -20℃

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H400
Precautionary Statements P273-P391
RIDADR UN 3077 9 / PGIII

 Synonyms

5'-methoxy-6'-(3-(pyrrolidin-1-yl)propoxy)spiro[cyclobutane-1,3'-indol]-2'-amine
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