Bexarotene structure
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Common Name | Bexarotene | ||
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CAS Number | 153559-49-0 | Molecular Weight | 348.478 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 489.7±44.0 °C at 760 mmHg | |
Molecular Formula | C24H28O2 | Melting Point | 230-231ºC | |
MSDS | Chinese USA | Flash Point | 229.5±23.1 °C |
Use of BexaroteneBexarotene is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma. |
Name | bexarotene |
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Synonym | More Synonyms |
Description | Bexarotene is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma. |
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Related Catalog | |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 489.7±44.0 °C at 760 mmHg |
Melting Point | 230-231ºC |
Molecular Formula | C24H28O2 |
Molecular Weight | 348.478 |
Flash Point | 229.5±23.1 °C |
Exact Mass | 348.208923 |
PSA | 37.30000 |
LogP | 8.55 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.556 |
Hazard Codes | Xn |
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RIDADR | NONH for all modes of transport |
Precursor 10 | |
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DownStream 0 |
Retinoids Bias Integrin Expression and Function in Cutaneous T-Cell Lymphoma.
J. Invest. Dermatol. 135 , 2102-8, (2015) Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of malignancies characterized by accumulation of malignant T-cells within the skin. Retinoids, metabolic derivatives, and synthetic analogs of... |
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RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.
Neurobiol. Dis. 82 , 132-40, (2015) We have recently demonstrated that short term bexarotene treatment of APP/PS1 mice significantly improves their cognitive performance. While there were no changes in plaque load, or insoluble Aβ level... |
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Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling.
J. Clin. Invest. 125(2) , 809-23, (2015) Osteoclasts are bone-resorbing cells that are important for maintenance of bone remodeling and mineral homeostasis. Regulation of osteoclast differentiation and activity is important for the pathogene... |
Targretin |
Bexarotene |
4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid |
LG 69 |
4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthalenyl)vinyl]benzoic acid |
Lg 1069 |
4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid |
Targretyn |
Bexaroten |
Targret |
Benzoic acid, 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]- |
4-[1-(3,5,5,8,8-Pentamethyl-2-5,8-dihydronaphthyl)vinyl]benzoic acid |
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid |
LGD1069 |