Heparastatin
Modify Date: 2024-01-10 16:44:13
Heparastatin structure
|
Common Name | Heparastatin | ||
|---|---|---|---|---|
| CAS Number | 153758-25-9 | Molecular Weight | 272.17900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H11F3N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HeparastatinHeparastatin is a heparanase inhibitor. |
| Name | (3S,4S,5R,6R)-4,5-dihydroxy-6-(trifluoroacetamido)piperidine-3-carboxylic acid hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Heparastatin is a heparanase inhibitor. |
|---|---|
| Related Catalog | |
| Target |
heparanase[1]. |
| In Vitro | Addition of 100 μM of Heparastatin (SF4) completely inhibits the enzyme activity of heparanase at a concentration of 0.15 μg/mL in an in vitro degradation assay. Addition of Heparastatin during the transition process does not affect the phenotypic change of TGF-β-treated cells[2]. |
| Cell Assay | Influence of a heparanase inhibitor on TGF-β3-induced EMT of NMuMG cells. NMuMG cells are cultured with 1 ng/mL TGF-β3 together with 10 or 100 μM Heparastatin (SF4) for 48 h[2]. |
| References |
| Molecular Formula | C8H11F3N2O5 |
|---|---|
| Molecular Weight | 272.17900 |
| Exact Mass | 272.06200 |
| PSA | 118.89000 |
| Hazard Codes | Xi |
|---|
| (3S,4S,5R,6R)-4,5-Dihydroxy-6-(2,2,2-trifluoro-acetylamino)-piperidine-3-carboxylic acid |
| (3S,4S,5R,6R)-6-(trifluoroacetamido)-4,5-dihydroxy-3-piperidinecarboxylic acid |
| (3S,4S,5R,6R)-6-(trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid |