Lys-γ3-MSH(human)

Modify Date: 2024-01-02 13:46:48

Lys-γ3-MSH(human) Structure
Lys-γ3-MSH(human) structure
 Common Name Lys-γ3-MSH(human)
CAS Number 156159-18-1 Molecular Weight 3018.245
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C128H193N45O39S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lys-γ3-MSH(human)


Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis[1][2].

 Names

Name L-Lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-L-glutamine
Synonym More Synonyms

 Lys-γ3-MSH(human) Biological Activity

Description Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC50 of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis[1][2].
Related Catalog
References

[1]. Harmer SC, Pepper DJ, Cooke K, Bennett HP, Bicknell AB. Evidence of a possible role for Lys-gamma3-MSH in the regulation of adipocyte function. J Endocrinol. 2008;196(1):149-158.

[2]. Bicknell KA, et al. Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity?. Mol Cell Endocrinol. 2009;300(1-2):71-76.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C128H193N45O39S
Molecular Weight 3018.245
Exact Mass 3016.422363
LogP -11.63
Index of Refraction 1.698

 Synonyms

L-Lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-seryl-L-seryl-L -serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-L-glutamine
L-Glutamine, L-lysyl-L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-seryl-L-se ryl-L-seryl-L-serylglycyl-L-seryl-L-serylglycyl-L-alanylglycyl-
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