Pheophorbide A

Modify Date: 2024-01-03 17:30:01

Pheophorbide A Structure
Pheophorbide A structure
Common Name Pheophorbide A
CAS Number 15664-29-6 Molecular Weight 592.68
Density 1.3±0.1 g/cm3 Boiling Point 1019.0±65.0 °C at 760 mmHg
Molecular Formula C35H36N4O5 Melting Point 191-195°C (lit.)
MSDS Chinese USA Flash Point 570.1±34.3 °C

 Use of Pheophorbide A


Pheophorbide A is an intermediate product in the chlorophyll degradation pathway and can be used as a photosensitizer. Pheophorbide A acts as a lymphovascular activator with antitumor activity[1].

 Names

Name pheophorbide a
Synonym More Synonyms

 Pheophorbide A Biological Activity

Description Pheophorbide A is an intermediate product in the chlorophyll degradation pathway and can be used as a photosensitizer. Pheophorbide A acts as a lymphovascular activator with antitumor activity[1].
Related Catalog
References

[1]. Jihye Kim, et al. Pheophorbide a identified in an Eupatorium perfoliatum extract is a novel lymphatic vascular activator. Biomed Pharmacother. 2022 Mar;147:112664.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1019.0±65.0 °C at 760 mmHg
Melting Point 191-195°C (lit.)
Molecular Formula C35H36N4O5
Molecular Weight 592.68
Flash Point 570.1±34.3 °C
Exact Mass 592.268555
PSA 136.97000
LogP 6.76
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.630

 Safety Information

Hazard Codes Xn
RIDADR NONH for all modes of transport

 Articles9

More Articles
Antioxidant-photosensitizer dual-loaded polymeric micelles with controllable production of reactive oxygen species.

Int. J. Pharm. 471(1-2) , 339-48, (2014)

Poly(ethylene glycol)-b-poly(caprolactone) (PEG-b-PCL) micelles dually loaded with both pheophorbide a (PhA) as a photosensitizer and β-carotene (CAR) as a singlet oxygen ((1)O2) scavenger were design...

In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells.

J. Pharm. Pharmacol. 67(2) , 170-7, (2015)

It has been reported that intestinal urate excretion is increased at chronic kidney disease (CKD) state. In this report, whether uremic toxins are involved in the upregulation of intestinal breast can...

ABCG2 transporter inhibitor restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy.

Sci. Rep. 5 , 13298, (2015)

Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast epithelial cells and a panel of ...

 Synonyms

Inchi=1/C35H36N4o5/C1-8-19-15(3)22-12-24-17(5)21(10-11-28(40)41)32(38-24)30-31(35(43)44-7)34(42)29-18(6)25(39-33(29)30)14-27-20(9-2)16(4)23(37-27)13-26(19)36-22/H8,12-14,17,21,31,36,39H,1,9-11H2,2-7H3,(H,40,41)/B22-12-,23-13-,24-12-,25-14-,26-13-,27-14
3-[(3S,4S,21R)-9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxophorbin-3-yl]propanoic acid
EINECS 239-738-5
[3s-(3alpha,4beta,21beta)]-ramethyl-20-oxo
3-phorbinepropanoicacid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tet
13-Epi-phaeophorbide-a
Rel-3-[(3R,4R)-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid
3-[(3S,4S,21R)-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid
3-Phorbinepropanoic acid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-,(3S,4S)
[3S-(3alpha,4beta,21beta)]-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic acid
(3S,4S)-9-Ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid
Pheophorbide A
(3S-(3a,4b,21b))-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic Acid
3-[(3S,4S,21R)-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinyl-3-phorbinyl]propanoic acid
3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-, (3S,4S,21R)-
Demagnesia chloric acid -a