Pheophorbide A
Modify Date: 2026-07-03 18:02:56
Pheophorbide A structure
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Common Name | Pheophorbide A | ||
|---|---|---|---|---|
| CAS Number | 15664-29-6 | Molecular Weight | 592.68 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1019.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C35H36N4O5 | Melting Point | 191-195°C (lit.) | |
| MSDS | Chinese USA | Flash Point | 570.1±34.3 °C | |
Use of Pheophorbide APheophorbide A is an intermediate product in the chlorophyll degradation pathway and can be used as a photosensitizer. Pheophorbide A acts as a lymphovascular activator with antitumor activity[1]. |
| Name | pheophorbide a |
|---|---|
| Synonym | More Synonyms |
| Description | Pheophorbide A is an intermediate product in the chlorophyll degradation pathway and can be used as a photosensitizer. Pheophorbide A acts as a lymphovascular activator with antitumor activity[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1019.0±65.0 °C at 760 mmHg |
| Melting Point | 191-195°C (lit.) |
| Molecular Formula | C35H36N4O5 |
| Molecular Weight | 592.68 |
| Flash Point | 570.1±34.3 °C |
| Exact Mass | 592.268555 |
| PSA | 136.97000 |
| LogP | 6.76 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.630 |
| InChIKey | RKEBXTALJSALNU-LDCXZXNSSA-N |
| SMILES | C=CC1=C(C)C2=NC1=CC1=NC(=CC3=C(C)C4=C(O)C(C(=O)OC)C(=C5NC(=C2)C(C)C5CCC(=O)O)C4=N3)C(CC)=C1C |
| Hazard Codes | Xn |
|---|---|
| RIDADR | NONH for all modes of transport |
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Antioxidant-photosensitizer dual-loaded polymeric micelles with controllable production of reactive oxygen species.
Int. J. Pharm. 471(1-2) , 339-48, (2014) Poly(ethylene glycol)-b-poly(caprolactone) (PEG-b-PCL) micelles dually loaded with both pheophorbide a (PhA) as a photosensitizer and β-carotene (CAR) as a singlet oxygen ((1)O2) scavenger were design... |
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In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells.
J. Pharm. Pharmacol. 67(2) , 170-7, (2015) It has been reported that intestinal urate excretion is increased at chronic kidney disease (CKD) state. In this report, whether uremic toxins are involved in the upregulation of intestinal breast can... |
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ABCG2 transporter inhibitor restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy.
Sci. Rep. 5 , 13298, (2015) Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast epithelial cells and a panel of ... |
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Name: Cytostatic activity against rat HTC cells at 66 ug/ml
Source: ChEMBL
Target: N/A
External Id: CHEMBL940480
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Name: Cytostatic activity against rat HTC cells at 33 ug/ml
Source: ChEMBL
Target: N/A
External Id: CHEMBL940479
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Name: Inhibition of soybean lipoxygenase at 100 uM
Source: ChEMBL
Target: Seed linoleate 9S-lipoxygenase
External Id: CHEMBL3123290
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Name: Selectivity for human KB-CPT cells to human KB cells
Source: ChEMBL
Target: KB
External Id: CHEMBL940476
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Name: Selectivity for human KB-VCR cells to human KB cells
Source: ChEMBL
Target: KB
External Id: CHEMBL940475
|
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Name: Cytostatic activity against rat HTC cells at 66 ug/ml under direct photoirradiation
Source: ChEMBL
Target: N/A
External Id: CHEMBL940478
|
|
Name: Cytostatic activity against rat HTC cells at 33 ug/ml under direct photoirradiation
Source: ChEMBL
Target: N/A
External Id: CHEMBL940477
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Name: Substrate Activity at ABCG2 (unknown origin) over expressed in MCF7/MX cells at 0.5 u...
Source: ChEMBL
Target: Broad substrate specificity ATP-binding cassette transporter ABCG2
External Id: CHEMBL4728754
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Name: Antiviral activity against HIV1 3B infected in human HOG.R5 assessed as inhibition of...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL1027472
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| Inchi=1/C35H36N4o5/C1-8-19-15(3)22-12-24-17(5)21(10-11-28(40)41)32(38-24)30-31(35(43)44-7)34(42)29-18(6)25(39-33(29)30)14-27-20(9-2)16(4)23(37-27)13-26(19)36-22/H8,12-14,17,21,31,36,39H,1,9-11H2,2-7H3,(H,40,41)/B22-12-,23-13-,24-12-,25-14-,26-13-,27-14 |
| 3-[(3S,4S,21R)-9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxophorbin-3-yl]propanoic acid |
| EINECS 239-738-5 |
| [3s-(3alpha,4beta,21beta)]-ramethyl-20-oxo |
| 3-phorbinepropanoicacid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tet |
| 13-Epi-phaeophorbide-a |
| Rel-3-[(3R,4R)-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid |
| 3-[(3S,4S,21R)-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid |
| 3-Phorbinepropanoic acid,9-ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-,(3S,4S) |
| [3S-(3alpha,4beta,21beta)]-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic acid |
| (3S,4S)-9-Ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid |
| Pheophorbide A |
| (3S-(3a,4b,21b))-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbine-3-propionic Acid |
| 3-[(3S,4S,21R)-14-Ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-9-vinyl-3-phorbinyl]propanoic acid |
| Demagnesia chloric acid -a |