Hosenkoside A

Modify Date: 2025-08-25 10:45:44

Hosenkoside A structure	Common Name	Hosenkoside A
	CAS Number	156791-82-1	Molecular Weight	979.153
	Density	1.4±0.1 g/cm3	Boiling Point	1075.9±65.0 °C at 760 mmHg
	Molecular Formula	C₄₈H₈₂O₂₀	Melting Point	N/A
	MSDS	N/A	Flash Point	604.5±34.3 °C

Use of Hosenkoside A

Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.

Name	8,19-Secolupane, β-D-glucopyranoside deriv.
Synonym	More Synonyms

Description	Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.
Related Catalog	Signaling Pathways >> Others >> Others Natural Products >> Saccharides and Glycosides Research Areas >> Inflammation/Immunology
In Vivo	The mean peak concentrations of hosenkoside A in rats after oral administration of total saponins of Semen Impatientis is 162.08±139.87 ng/mL, occurring at times of 0.67 h. The terminal half-lives of hosenkoside A is 5.39±2.06h[1].
Animal Admin	Male Wistar rats (7 weeks old, 220±20 g, n=6) are fasted for 12 h. Total saponins of Semen Impatientis at a dose of 300 mg (in 10 mL)/kg are orally administered to rats using a gastric gavage tube. The doses of hosenkoside A is12.4 mg/kg for an oral dose of 300 mg/kg total saponins. Blood samples (0.20 mL) are collected from suborbital vein into heparinized tubes before administration (0 min), and 0.08, 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 12 and 24 h after dosing.
References	[1]. Yu X, et al. An LC-MS/MS method for simultaneous determination of hosenkoside A and hosenkoside K from Semen Impatientis in rat plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2017 Mar;31(3).

Density	1.4±0.1 g/cm3
Boiling Point	1075.9±65.0 °C at 760 mmHg
Molecular Formula	C₄₈H₈₂O₂₀
Molecular Weight	979.153
Flash Point	604.5±34.3 °C
Exact Mass	978.539917
PSA	327.60000
LogP	0.07
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.626
InChIKey	JUKFJOYCFLIWIA-MDQYKXRHSA-N
SMILES	CC(CO)C1CCC2(CCC3(C)C(CCC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6OC6OC(CO)C(O)C(O)C6O)C(C)(COC6OC(CO)C(O)C(O)C6O)C5CCC43C)C2O)CO1
Storage condition	2-8℃

β-D-Glucopyranoside, (1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-glucopyranosyloxy)methyl]octadecahydro-1-hydroxy-6'-[(1S)-2-hydroxy-1-methylethyl]-4a,4b,7,10a-tetramethylspiro[chrysene -2(1H),3'(4'H)-[2H]pyran]-8-yl 2-O-β-D-glucopyranosyl-

(1R,2S,4aR,4bR,6'S,6aR,7R,8S,10aR,10bR,12aS)-7-[(β-D-Glucopyranosyloxy)methyl]-1-hydroxy-6'-[(2S)-1-hydroxy-2-propanyl]-4a,4b,7,10a-tetramethyloctadecahydro-1H,4'H-spiro[chrysene-2,3'-pyran]-8-yl 2 -O-β-D-glucopyranosyl-β-D-glucopyranoside

Hosenkoside A