DDR2-IN-1

Modify Date: 2025-08-31 15:27:19

DDR2-IN-1 Structure
DDR2-IN-1 structure
Common Name DDR2-IN-1
CAS Number 1573053-23-2 Molecular Weight 526.03
Density N/A Boiling Point N/A
Molecular Formula C27H32ClN5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DDR2-IN-1


DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1].

 Names

Name 4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide

 DDR2-IN-1 Biological Activity

Description DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1].
Related Catalog
Target

IC50: 26 nM (DDR2)[1]

References

[1]. Margarita Wucherer-Plietker, et al. Inhibiteurs de ddr2 pour le traitement de l'arthrose. Patent WO2014032755A2.

 Chemical & Physical Properties

Molecular Formula C27H32ClN5O4
Molecular Weight 526.03
InChIKey YKRARSYSXDHLJH-UHFFFAOYSA-N
SMILES CNC(=O)c1cc(Oc2ccc(CNC(=O)Nc3cc(C)c(Cl)cc3OCCN(C)C)cc2C)ccn1
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