MK 386

Modify Date: 2025-08-28 08:17:56

MK 386 Structure
MK 386 structure
Common Name MK 386
CAS Number 158493-17-5 Molecular Weight 415.69
Density 0.951g/cm3 Boiling Point 505.2ºC at 760mmHg
Molecular Formula C28H49NO Melting Point N/A
MSDS N/A Flash Point 203.9ºC

 Use of MK 386


MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].

 Names

Name 4,6,9a,11a-tetramethyl-1-(6-methylheptan-2-yl)-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-7-one

 MK 386 Biological Activity

Description MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].
Related Catalog
Target

5-α-reductase I[1]

References

[1]. Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11.  

 Chemical & Physical Properties

Density 0.951g/cm3
Boiling Point 505.2ºC at 760mmHg
Molecular Formula C28H49NO
Molecular Weight 415.69
Flash Point 203.9ºC
Exact Mass 415.38100
PSA 20.31000
LogP 7.11230
Vapour Pressure 2.48E-10mmHg at 25°C
Index of Refraction 1.494
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