bio-THZ1

Modify Date: 2024-01-26 19:15:59

bio-THZ1 Structure
bio-THZ1 structure
Common Name bio-THZ1
CAS Number 1604811-14-4 Molecular Weight 1053.67
Density N/A Boiling Point N/A
Molecular Formula C52H65ClN12O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of bio-THZ1


bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].

 Names

Name bio-THZ1

 bio-THZ1 Biological Activity

Description bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].
Related Catalog
Target

CDK7[1].

References

[1]. Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20.

 Chemical & Physical Properties

Molecular Formula C52H65ClN12O8S
Molecular Weight 1053.67
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