Cromoglicic acid

Modify Date: 2024-01-02 14:31:19

Cromoglicic acid Structure
Cromoglicic acid structure
Common Name Cromoglicic acid
CAS Number 16110-51-3 Molecular Weight 468.37
Density 1.623 Boiling Point 752.3ºC at 760 mmHg
Molecular Formula C23H16O11 Melting Point 241-242ºC
MSDS N/A Flash Point 263.9ºC

 Use of Cromoglicic acid


Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis[1].

 Names

Name cromoglycic acid
Synonym More Synonyms

 Cromoglicic acid Biological Activity

Description Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis[1].
Related Catalog
References

[1]. Minutello K, et al. Cromolyn Sodium.

 Chemical & Physical Properties

Density 1.623
Boiling Point 752.3ºC at 760 mmHg
Melting Point 241-242ºC
Molecular Formula C23H16O11
Molecular Weight 468.37
Flash Point 263.9ºC
Exact Mass 468.06900
PSA 173.71000
LogP 2.11450
Vapour Pressure 1.08E-23mmHg at 25°C
Index of Refraction 1.681

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ2365000
CHEMICAL NAME :
4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo-
CAS REGISTRY NUMBER :
16110-51-3
LAST UPDATED :
199606
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H16-O11
MOLECULAR WEIGHT :
468.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4407810

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
WGK Germany 2
RTECS DJ2380000
HS Code 2922499990

 Synthetic Route

~64%

Cromoglicic acid Structure

Cromoglicic acid

CAS#:16110-51-3

Literature: REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. Patent: US2010/94026 A1, 2010 ; Location in patent: Page/Page column 7-8 ;

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Synonyms

Acidum cromoglicicum
cromolyn
EINECS 240-279-8
Nalcrom
Acide cromoglicique
1,3-bis(2-carboxychromon-5-yloxy)-2-hydroxy propane
1,3-bis(2-carboxy-chromon-5-yloxy)-propan-2-ol
5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid
MFCD00057744
Cromoglicic acid
Cromoglycate
Acido cromoglicico
5,5'-(2-hydroxypropane-1,3-diyl)bis(oxy)bis(4-oxo-4H-chromene-2-carboxylic acid)
Lomudal
Lomusol
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