MC-Val-Cit-PAB-vinblastine

Modify Date: 2025-08-27 19:01:52

MC-Val-Cit-PAB-vinblastine Structure
MC-Val-Cit-PAB-vinblastine structure
Common Name MC-Val-Cit-PAB-vinblastine
CAS Number 2055896-92-7 Molecular Weight 1366.62
Density N/A Boiling Point N/A
Molecular Formula C74H97N10O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Val-Cit-PAB-vinblastine


MC-Val-Cit-PAB-vinblastine has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-vinblastine is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].

 Names

Name MC-Val-Cit-PAB-vinblastine

 MC-Val-Cit-PAB-vinblastine Biological Activity

Description MC-Val-Cit-PAB-vinblastine has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-vinblastine is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].
Related Catalog
References

[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

 Chemical & Physical Properties

Molecular Formula C74H97N10O15
Molecular Weight 1366.62
InChIKey UIGOTWKBGXIMLH-RWNFVDQVSA-O
SMILES CCC1(O)CC2CC(C(=O)OC)(c3cc4c(cc3OC)N(C)C3C(O)(C(=O)OC)C(OC(C)=O)C5(CC)C=CCN6CCC43C65)c3[nH]c4ccccc4c3CC[N+](Cc3ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCCCCN4C(=O)C=CC4=O)C(C)C)cc3)(C2)C1
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