MC-Val-Cit-PAB-carfilzomib

Modify Date: 2025-08-25 19:15:54

MC-Val-Cit-PAB-carfilzomib Structure
MC-Val-Cit-PAB-carfilzomib structure
Common Name MC-Val-Cit-PAB-carfilzomib
CAS Number 2055896-83-6 Molecular Weight 1275.56
Density N/A Boiling Point N/A
Molecular Formula C68H96N11O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Val-Cit-PAB-carfilzomib


MC-Val-Cit-PAB-carfilzomib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-carfilzomib is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].

 Names

Name MC-Val-Cit-PAB-carfilzomib

 MC-Val-Cit-PAB-carfilzomib Biological Activity

Description MC-Val-Cit-PAB-carfilzomib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Val-Cit-PAB-carfilzomib is used for the antibody-drug conjugates (ADC) that are effective and stable in vitro and in vivo to treat various diseases or disorders[1].
Related Catalog
References

[1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

 Chemical & Physical Properties

Molecular Formula C68H96N11O13
Molecular Weight 1275.56
InChIKey LZSSFWVHVYJCSL-FWDVWTIGSA-N
SMILES CC(C)CC(NC(=O)C(CCc1ccccc1)NC(=O)C[N+]1(Cc2ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCCCCN3C(=O)C=CC3=O)C(C)C)cc2)CCOCC1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1.[I-]
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