Lupeol acetate

Modify Date: 2024-01-02 12:40:51

Lupeol acetate Structure
Lupeol acetate structure
Common Name Lupeol acetate
CAS Number 1617-68-1 Molecular Weight 468.75400
Density 1.01g/cm3 Boiling Point 502.7ºC at 760mmHg
Molecular Formula C32H52O2 Melting Point 218ºC
MSDS N/A Flash Point 254.7ºC

 Use of Lupeol acetate


Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].

 Names

Name [(1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-yl] acetate
Synonym More Synonyms

 Lupeol acetate Biological Activity

Description Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].
Related Catalog
References

[1]. Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.

 Chemical & Physical Properties

Density 1.01g/cm3
Boiling Point 502.7ºC at 760mmHg
Melting Point 218ºC
Molecular Formula C32H52O2
Molecular Weight 468.75400
Flash Point 254.7ºC
Exact Mass 468.39700
PSA 26.30000
LogP 8.59560
Vapour Pressure 3.1E-10mmHg at 25°C
Index of Refraction 1.524

 Safety Information

Hazard Codes Xi

 Synonyms

3-O-acetyl-lupeol
lup-20(29)-en-3-yl acetate
(3beta)-lup-20(29)-en-3-yl acetate
lupeol acetate
3-acetoxy-28-deoxobetulin
3-Acetyllupeol
Lupeyl acetate
LUPENYL ACETATE
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