BM-1244
Modify Date: 2025-09-18 10:48:07
BM-1244 structure
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Common Name | BM-1244 | ||
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| CAS Number | 1619923-32-8 | Molecular Weight | 1159.79 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C54H59ClF4N6O8S4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BM-1244BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC50 of 5 nM. (From patent WO2019033119A1)[1]. |
| Name | BM-1244 |
|---|
| Description | BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC50 of 5 nM. (From patent WO2019033119A1)[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C54H59ClF4N6O8S4 |
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| Molecular Weight | 1159.79 |
| InChIKey | OGHPBBHWAPIYHS-VZUYHUTRSA-N |
| SMILES | Cc1c(S(C)(=O)=O)c(-c2cc(F)cc(N3CCN(c4ccc(NS(=O)(=O)c5ccc(NC(CCN6CCC(C(=O)O)CC6)CSc6ccccc6)c(S(=O)(=O)C(F)(F)F)c5)cc4)CC3)c2)c(-c2ccc(Cl)cc2)n1C(C)C |