DLK-IN-1
Modify Date: 2024-02-04 22:37:31
DLK-IN-1 structure
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Common Name | DLK-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1620574-24-4 | Molecular Weight | 423.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24F3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DLK-IN-1DLK-IN-1 is a selective inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimer’s Disease. |
| Name | DLK-IN-1 |
|---|
| Description | DLK-IN-1 is a selective inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimer’s Disease. |
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| Related Catalog | |
| Target |
Ki: 3 nM (DLK)[1]. |
| References |
| Molecular Formula | C20H24F3N5O2 |
|---|---|
| Molecular Weight | 423.43 |
| Storage condition | 2-8℃ |