1-(Fmoc-amino)cyclohexanecarboxylic acid

Modify Date: 2024-01-20 14:16:40

1-(Fmoc-amino)cyclohexanecarboxylic acid Structure
1-(Fmoc-amino)cyclohexanecarboxylic acid structure
Common Name 1-(Fmoc-amino)cyclohexanecarboxylic acid
CAS Number 162648-54-6 Molecular Weight 365.422
Density 1.3±0.1 g/cm3 Boiling Point 591.7±29.0 °C at 760 mmHg
Molecular Formula C22H23NO4 Melting Point 185-187 °C
MSDS Chinese USA Flash Point 311.7±24.3 °C

 Names

Name 1-(fmoc-amino)cyclohexanecarboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 591.7±29.0 °C at 760 mmHg
Melting Point 185-187 °C
Molecular Formula C22H23NO4
Molecular Weight 365.422
Flash Point 311.7±24.3 °C
Exact Mass 365.162720
PSA 75.63000
LogP 4.73
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.637
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2924299090

 Synthetic Route

~65%

1-(Fmoc-amino)cyclohexanecarboxylic acid Structure

1-(Fmoc-amino)c...

CAS#:162648-54-6

Literature: Lescrinier, Theo; Hendrix, Chris; Kerremans, Luc; Rozenski, Jef; Link, Andreas; Samyn, Bart; Van Aerschot, Arthur; Lescrinier, Eveline; Eritja, Ramon; Van Beeumen, Jozef; Herdewijn, Piet Chemistry - A European Journal, 1998 , vol. 4, # 3 p. 425 - 433

~5%

1-(Fmoc-amino)cyclohexanecarboxylic acid Structure

1-(Fmoc-amino)c...

CAS#:162648-54-6

Literature: American Home Products Corporation Patent: US5385910 A1, 1995 ;

~71%

1-(Fmoc-amino)cyclohexanecarboxylic acid Structure

1-(Fmoc-amino)c...

CAS#:162648-54-6

Literature: Babu, Vommina V. Suresh; Ananda, Kuppanna Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2001 , vol. 40, # 1 p. 70 - 74

~47%

1-(Fmoc-amino)cyclohexanecarboxylic acid Structure

1-(Fmoc-amino)c...

CAS#:162648-54-6

Literature: Galoppini, Claudia; Meini, Stefania; Tancredi, Mariella; Di Fenza, Armida; Triolo, Antonio; Quartara, Laura; Maggi, Carlo A.; Formaggio, Fernando; Toniolo, Claudio; Mazzucco, Silvia; Papini, Annamaria; Rovero, Paolo Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 409 - 414

~18%

1-(Fmoc-amino)cyclohexanecarboxylic acid Structure

1-(Fmoc-amino)c...

CAS#:162648-54-6

Literature: Novartis AG Patent: US6353017 B1, 2002 ; Location in patent: Page column 25-26 ; US 6353017 B1

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles2

More Articles
A.P. Combs et al.

J. Am. Chem. Soc. 118 , 287, (1996)

T. Lescrinier et al.

Chemistry 4 , 425, (1998)

 Synonyms

1-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}cyclohexanecarboxylic acid
1-(9H-fluoren-9-ylmethoxycarbonylamino)cyclohexane-1-carboxylic acid
Cyclohexanecarboxylic acid, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-
Fmoc-homocycloleucine
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclohexanecarboxylic acid
N-Fmoc-1-amino-1-cyclohexanecarboxylic acid
MFCD00273464
1-(Fmoc-amino)cyclohexanecarboxylic acid
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