IDH-305
Modify Date: 2024-01-11 17:38:53
IDH-305 structure
|
Common Name | IDH-305 | ||
|---|---|---|---|---|
| CAS Number | 1628805-46-8 | Molecular Weight | 490.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H22F4N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IDH-305IDH-305 is an inhibitor of isocitrate dehydrogenase (IDH). |
| Name | IDH-305 |
|---|---|
| Synonym | More Synonyms |
| Description | IDH-305 is an inhibitor of isocitrate dehydrogenase (IDH). |
|---|---|
| Related Catalog | |
| Target |
IDH[1] |
| In Vitro | IDH-305 is an inhibitor of isocitrate dehydrogenase (IDH). Isocitrate dehydrogenase (IDH) is an essential enzyme for cellular respiration in the tricarboxylic acid (TCA) cycle. The IDH1 inhibitor IDH-305 has entered an ongoing phase 1 clinical trial (NCT02381886) for patients with IDH1-R132 mutant advanced hematologic or solid malignancies[1]. |
| References |
| Molecular Formula | C23H22F4N6O2 |
|---|---|
| Molecular Weight | 490.46 |
| Storage condition | 2-8℃ |
| (4R)-4-[(1S)-1-fluoroethyl]-3-(2-{[(1S)-1-[4-methyl-2'-(trifluoromethyl)-[3,4'-bipyridin]-6-yl]ethyl]amino}pyrimidin-4-yl)-1,3-oxazolidin-2-one |